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            Under the collaboration, SystImmune and Bristol Myers Squibb will co-develop and co-commercialize BL-B01D1, a potentially first-in-class bispecific EGFRxHER3 ADC with potential to treat patients with lung and breast cancer, in the United States.

            Lead Product(s): BL-B01D1

            Therapeutic Area: Oncology Product Name: BL-B01D1

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: Bristol Myers Squibb

            Deal Size: $8,400.0 million Upfront Cash: $800.0 million

            Deal Type: Collaboration December 11, 2023

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            Details:

            BL-B01D1 is a first-in-class bispecific antibody-drug conjugate (ADC) developed by SystImmune, targeting both EGFR and HER3, proteins that are highly expressed in most epithelial tumors in individuals with Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC).

            Lead Product(s): BL-B01D1

            Therapeutic Area: Oncology Product Name: BL-B01D1

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 12, 2023

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            BL-B01D1 is a first-in-class bispecific antibody-drug conjugate developed by SystImmune, targeting both EGFR and HER3, proteins that are highly expressed in most epithelial tumors.

            Lead Product(s): BL-B01D1,Osimertinib Mesylate

            Therapeutic Area: Oncology Product Name: BL-B01D1

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 01, 2023

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