Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
SparingVision Completes Final Dose Escalation in PRODYGY Trial with SPVN06
Details : SPVN06 is a mutation-agnostic AAV gene therapy approach comprising one neurotrophic factor (RdCVF) and one enzyme reducing oxidative stress. It is under development for treating Retinitis Pigmentosa.
Product Name : SPVN06
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 24, 2024
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SPVN20
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Tenpoint Therapeutics
Deal Size : Undisclosed
Deal Type : Divestment
SparingVision Sells Ex Vivo GIRK Technology to Tenpoint Therapeutics
Details : Through the divestment, Tenpoint has acquired SparingVision's ex vivo GIRK technology. SparingVision will remain focused on in vivo genomic medicines, with SPVN20, a GIRK-based gene therapy candidate.
Product Name : SPVN20
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 07, 2023
Lead Product(s) : SPVN20
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Tenpoint Therapeutics
Deal Size : Undisclosed
Deal Type : Divestment
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SPVN06 is a proprietary, mutation-agnostic, AAV gene therapy approach comprised of one neurotrophic factor and one enzyme reducing oxidative stress used for the treatment of for the treatment of retinitis pigmentosa.
Product Name : SPVN06
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 30, 2023
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Jeito Capital
Deal Size : $75.0 million
Deal Type : Series B Financing
Details : Proceeds from the financing will be used to fund the first-in-human trials of the Company’s two lead gene-independent assets, SPVN06 and SPVN20, as well as the development of genome editing assets through its collaboration with Intellia Therapeutics.
Product Name : SPVN06
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 14, 2022
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Jeito Capital
Deal Size : $75.0 million
Deal Type : Series B Financing
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SPVN06 is a proprietary, mutation-agnostic, AAV gene therapy approach comprised of one neurotrophic factor and one enzyme reducing oxidative stress which, acting synergistically, aim at slowing or stopping the degeneration of cone photoreceptors.
Product Name : SPVN06
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 12, 2022
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : 4BIO Capital
Deal Size : $51.9 million
Deal Type : Financing
SparingVision Raises €44.5 Million and Appoints Stéphane Boissel as Chief Executive Officer
Details : Proceeds from the financing will be primarily used to advance the development of SparingVision’s breakthrough treatment SPVN06 for the mutation-agnostic treatment of retinitis pigmentosa.
Product Name : SPVN06
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 21, 2020
Lead Product(s) : SPVN06
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : 4BIO Capital
Deal Size : $51.9 million
Deal Type : Financing
Lead Product(s) : SPVN06
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SPVN06 uses a gene therapy-based approach independent of mutated genes and by a single subretinal injection of proprietary neurotrophic factors, aims at stopping and preventing the degeneration of photoreceptors leading to blindness.
Product Name : SPVN06
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 30, 2020
Lead Product(s) : SPVN06
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable