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Find Clinical Drug Pipeline Developments & Deals by SparingVision

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : SPVN06 is a mutation-agnostic AAV gene therapy approach comprising one neurotrophic factor (RdCVF) and one enzyme reducing oxidative stress. It is under development for treating Retinitis Pigmentosa.

                          Product Name : SPVN06

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 24, 2024

                          Lead Product(s) : SPVN06

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : Through the divestment, Tenpoint has acquired SparingVision's ex vivo GIRK technology. SparingVision will remain focused on in vivo genomic medicines, with SPVN20, a GIRK-based gene therapy candidate.

                          Product Name : SPVN20

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 07, 2023

                          Lead Product(s) : SPVN20

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : Tenpoint Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Divestment

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                          03

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : SPVN06 is a proprietary, mutation-agnostic, AAV gene therapy approach comprised of one neurotrophic factor and one enzyme reducing oxidative stress used for the treatment of for the treatment of retinitis pigmentosa.

                          Product Name : SPVN06

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          August 30, 2023

                          Lead Product(s) : SPVN06

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : Proceeds from the financing will be used to fund the first-in-human trials of the Company’s two lead gene-independent assets, SPVN06 and SPVN20, as well as the development of genome editing assets through its collaboration with Intellia Therapeutics.

                          Product Name : SPVN06

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 14, 2022

                          Lead Product(s) : SPVN06

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : Jeito Capital

                          Deal Size : $75.0 million

                          Deal Type : Series B Financing

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                          05

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : SPVN06 is a proprietary, mutation-agnostic, AAV gene therapy approach comprised of one neurotrophic factor and one enzyme reducing oxidative stress which, acting synergistically, aim at slowing or stopping the degeneration of cone photoreceptors.

                          Product Name : SPVN06

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 12, 2022

                          Lead Product(s) : SPVN06

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : Proceeds from the financing will be primarily used to advance the development of SparingVision’s breakthrough treatment SPVN06 for the mutation-agnostic treatment of retinitis pigmentosa.

                          Product Name : SPVN06

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 21, 2020

                          Lead Product(s) : SPVN06

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : 4BIO Capital

                          Deal Size : $51.9 million

                          Deal Type : Financing

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                          07

                          CST
                          Not Confirmed
                          CST
                          Not Confirmed

                          Details : SPVN06 uses a gene therapy-based approach independent of mutated genes and by a single subretinal injection of proprietary neurotrophic factors, aims at stopping and preventing the degeneration of photoreceptors leading to blindness.

                          Product Name : SPVN06

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          June 30, 2020

                          Lead Product(s) : SPVN06

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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