Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cerevance Doses First Patient in Phase 3 ARISE Trial for Parkinson’s Disease
Details : CVN424 (solengepras) is a first-in-class non-dopamine therapy that selectively modulates GPR6, being investigated for the treatment option for individuals with early-stage Parkinson’s disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 18, 2024
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 14, 2024
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Agent Capital
Deal Size : $98.0 million
Deal Type : Series B Financing
Cerevance Adds $47 Million in Series B-1 Extension to Advance Robust Clinical Pipeline
Details : The financing is intended to support the clinical development of CVN424, which is being investigated as a treatment option for individuals with early-stage Parkinson’s disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 25, 2024
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Agent Capital
Deal Size : $98.0 million
Deal Type : Series B Financing
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CVN424 is a first-in-class non-dopamine therapy that selectively modulates GPR6, an orphan G-protein coupled receptor, which is investigated for the treatment option for individuals with early-stage Parkinson’s disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 13, 2023
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Early Parkinson's Disease Monotherapy With CVN424
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 23, 2023
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Gates Frontier
Deal Size : $116.0 million
Deal Type : Series B Financing
Cerevance Expands Series B Financing with Additional $51 Million
Details : The financing will support upcoming clinical trials focused on Parkinson’s disease, Amyotrophic Lateral Sclerosis, and schizophrenia including CVN424, a first-in-class, oral, brain penetrant, non-dopaminergic, GPR6 inverse agonist in Phase 2 trial for ...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 13, 2023
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Gates Frontier
Deal Size : $116.0 million
Deal Type : Series B Financing
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Relative Bioavailability and Food Effect Study of CVN424
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 02, 2022
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CVN424 showed a 1.3-hour improvement in OFF time compared to placebo (p=0.042) at four weeks. This was accompanied by an increase in ON time without Troublesome Dyskinesia, without a meaningful worsening of ON time with Troublesome Dyskinesia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 31, 2022
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Google Ventures
Deal Size : $45.0 million
Deal Type : Series B Financing
Gates, GV Chip into $45M Round for CNS biotech Cerevance
Details : The proceeds will advance the company's lead Parkinson's disease plan into phase 2 and move other prospects into the clinic from earlier stages.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 14, 2020
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Google Ventures
Deal Size : $45.0 million
Deal Type : Series B Financing
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of CVN424 in Parkinson's Disease Patients With Motor Fluctuations
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 10, 2019
Lead Product(s) : Solengepras
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable