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    [{"orgOrder":0,"company":"Sernova","sponsor":"Evotec","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2022","type":"Financing","leadProduct":"Human Donor Islet Cell","moa":"||Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0.27000000000000002,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0.27000000000000002,"dosageForm":"Implant","sponsorNew":"Sernova \/ Evotec","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Evotec"},{"orgOrder":0,"company":"Sernova","sponsor":"Evotec","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2023","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"||Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Evotec","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Evotec"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2023","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"||Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2023","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Human Donor Islet Cell","moa":"Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"Eledon Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2025","type":"Agreement","leadProduct":"Human Donor Islet Cell","moa":"||Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Eledon Pharmaceuticals","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Eledon Pharmaceuticals"},{"orgOrder":0,"company":"Sernova","sponsor":"Icon Plc | University of Chicago | Breakthrough T1D","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2018","type":"Inapplicable","leadProduct":"Sernova Cell Pouch","moa":"Insulin hormone","graph1":"Endocrinology","graph2":"Phase I\/ Phase II","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Icon Plc | University of Chicago | Breakthrough T1D","highestDevelopmentStatusID":"7","companyTruncated":"Sernova \/ Icon Plc | University of Chicago | Breakthrough T1D"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Thyroid Cell","moa":"T3\/T4","graph1":"Endocrinology","graph2":"IND Enabling","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Sernova \/ Undisclosed"},{"orgOrder":0,"company":"Sernova","sponsor":"AgeX Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2020","type":"Collaboration","leadProduct":"Recombinant Pluripotent Stem Cell-Derived Pancreatic Islet Beta Cell","moa":"Undisclosed","graph1":"Endocrinology","graph2":"Undisclosed","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sernova \/ Sernova","highestDevelopmentStatusID":"1","companyTruncated":"Sernova \/ Sernova"},{"orgOrder":0,"company":"Sernova","sponsor":"Evotec","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"GERMANY","productType":"Undisclosed","year":"2022","type":"Partnership","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Endocrinology","graph2":"Preclinical","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Sernova \/ Sernova","highestDevelopmentStatusID":"4","companyTruncated":"Sernova \/ Sernova"},{"orgOrder":0,"company":"Sernova","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Undisclosed","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Endocrinology","graph2":"Preclinical","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sernova \/ AstraZeneca","highestDevelopmentStatusID":"4","companyTruncated":"Sernova \/ AstraZeneca"},{"orgOrder":0,"company":"Sernova","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"CANADA","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Endocrinology","graph2":"IND Enabling","graph3":"Sernova","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sernova \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Sernova \/ Undisclosed"}]

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                            01

                            Sernova

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                            AIChE Annual Meeting
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                            Sernova

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                            Lead Product(s) : Human Donor Islet Cell,Tegoprubart

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Eledon Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Sernova Collaboration with Eledon to Advance a Cure for Type 1 Diabetes

                            Details : Under the agreement, Eledon will supply tegoprubart to be used as Immunosuppressive Agent in Sernova’s Phase 1/2 Cell Pouch Bio-hybrid Organ Clinical Trial in Patients with Type 1 Diabetes.

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            July 09, 2025

                            Lead Product(s) : Human Donor Islet Cell,Tegoprubart

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Eledon Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            02

                            Sernova

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                            AIChE Annual Meeting
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                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova Reveals Interim Data for Cell Pouch Bio-Organ in Type 1 Diabetes

                            Details : Sernova is focused on developing it’s Cell Pouch Bio-hybrid Organ as a functional cure for type 1 diabetes in patients with hypoglycemia unawareness and a history of severe hypoglycemic episodes.

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            May 14, 2025

                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Sernova

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                            AIChE Annual Meeting
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                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova Updates Phase 1/2 Trial of Cell Pouch for Type 1 Diabetes

                            Details : Sernova is focused on developing it’s Cell Pouch Bio-hybrid Organ as a functional cure for type 1 diabetes in patients with hypoglycemia unawareness and a history of severe hypoglycemic episodes.

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            April 01, 2025

                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Sernova

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                            AIChE Annual Meeting
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Endocrinology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova gets FDA IND Clearance for Cell Pouch with Autograft Thyroid Cells

                            Details : Company’s Cell Pouch with auto-transplanted thyroid cells is being evaluated in patients undergoing thyroid surgery for nodular thyroid disease.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 03, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Endocrinology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Sernova

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                            AIChE Annual Meeting
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                            Sernova

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                            Lead Product(s) : Thyroid Cell

                            Therapeutic Area : Endocrinology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova Submits IND for Cell Pouch Bio-Hybrid Organ in Hypothyroidism

                            Details : Company’s Cell Pouch auto-transplanted with thyroid cells is being investigated for nodular thyroid disease. It restores thyroxine and triiodothyronine, to pre-thyroidectomy levels.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            February 03, 2025

                            Lead Product(s) : Thyroid Cell

                            Therapeutic Area : Endocrinology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Sernova

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                            AIChE Annual Meeting
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Sponsor : AstraZeneca

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Sernova Announces Research Collaboration with AstraZeneca to Evaluate Novel Potential Therapeutic Cell Applica...

                            Details : Under the collaboration, AstraZeneca will explore the use of Sernova’s Cell Pouch System as a potential platform for integration with its development of the next wave of innovative cell therapies for various indications.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            May 03, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Sponsor : AstraZeneca

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Sernova

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                            AIChE Annual Meeting
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                            Sernova

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                            Lead Product(s) : Human Donor Islet Cell,Undisclosed

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova Announces Initial Islet Transplantation in First Two Patients Enrolled in Second Cohort of its U.S. Ph...

                            Details : Sernova’s Cell Pouch System™ (human donor islets cell) is a novel implantable and scalable medical device which forms a natural environment in the body for the housing and long-term survival and function of therapeutic cells.

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            March 08, 2023

                            Lead Product(s) : Human Donor Islet Cell,Undisclosed

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Sernova

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                            AIChE Annual Meeting
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                            Sernova

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                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova Announces Advancements with its Novel Cell Pouch System to Preserve Thyroid Function Following Total T...

                            Details : Sernova’s Cell Pouch System is a novel implant consisting human islets cells, which allows for reestablishment of production of triiodothyronine (T3) and thyroxine (T4) and the hypothalamic-pituitary-thyroid axis, to preserve thyroid function following...

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            January 30, 2023

                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Sernova

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                            AIChE Annual Meeting
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                            Sernova

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                            Lead Product(s) : Human Donor Islet Cell,Undisclosed

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Evotec

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova and Evotec on Track to Initiate Clinical Testing of the First iPSC-Derived Islets in Cell Pouch as a P...

                            Details : Sernova’s Cell Pouch System™ (human donor islets cell) is a novel implantable and scalable medical device which forms a natural environment in the body for the housing and long-term survival and function of therapeutic cells.

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            January 10, 2023

                            Lead Product(s) : Human Donor Islet Cell,Undisclosed

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Evotec

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Sernova

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                            AIChE Annual Meeting
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                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sernova Announces First Two Patients Implanted with Cell Pouch™ in the Second Cohort of its US Phase 1/2 Cli...

                            Details : Human Donor Islets Cell are transplanted into the Sernova Cell Pouch approximately six weeks after Cell Pouch implantation to allow development of fully vascularized native tissue chambers and achieve a stable immunosuppressant regimen.

                            Product Name : Sernova Cell Pouch

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            November 17, 2022

                            Lead Product(s) : Human Donor Islet Cell

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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