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    [{"orgOrder":0,"company":"Scorpion Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"STX-721","moa":"EGFR","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Scorpion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Scorpion Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Scorpion Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Scorpion Therapeutics","sponsor":"Pierre Fabre","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"STX-721","moa":"EGFR","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Scorpion Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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Platform","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Scorpion Therapeutics \/ AstraZeneca","highestDevelopmentStatusID":"3","companyTruncated":"Scorpion Therapeutics \/ AstraZeneca"}]

    Find Clinical Drug Pipeline Developments & Deals by Scorpion Therapeutics

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                            01

                            Scorpion Therapeutics

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                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $2,500.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Eli Lilly to Buy Scorpion Therapeutics' Cancer Therapy for up to $2.5 Billion

                            Details : The acquisition will expand Lilly's oncology pipeline with STX-478, the differentiated and potentially best-in-class, mutant-selective PI3Kα inhibitor for the treating breast cancer.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $2,500.0 million

                            January 13, 2025

                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $2,500.0 million

                            Deal Type : Acquisition

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                            02

                            Scorpion Therapeutics

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                            Scorpion Therapeutics

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                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics Provides Updates on STX-478, PI3Kα Inhibitor

                            Details : STX-478 is a mutant-selective PI3Kα inhibitor drug candidate, which is being evaluated for the treatment of breast cancer as a monotherapy and in combination with fulvestrant.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 10, 2024

                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Scorpion Therapeutics

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                            Lead Product(s) : STX-241

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Pierre Fabre

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pierre Fabre & Scorpion Dose First Patient in PFL-241/STX-241 Lung Cancer Trial

                            Details : PFL-241/STX-241 is an oral therapy designed to selectively inhibit the C797S resistance mutation. It is currently being investigated for the treatment of locally advanced or metastatic NSCLC.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 08, 2024

                            Lead Product(s) : STX-241

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Pierre Fabre

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Scorpion Therapeutics

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                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Willett Advisors

                            Deal Size : $150.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Scorpion Wins $150M Financing to Advance Precision Oncology Pipeline

                            Details : The Proceeds support further mid-stage clinical development of STX-478, mutant-selective PI3Kα program for treating breast cancer as a monotherapy and in combination with Fulvestrant.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            July 16, 2024

                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Willett Advisors

                            Deal Size : $150.0 million

                            Deal Type : Series C Financing

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                            05

                            Scorpion Therapeutics

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                            Scorpion Therapeutics

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                            Lead Product(s) : STX-721

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Pierre Fabre

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics and Pierre Fabre Laboratories Announce First Patient Dosed in Phase 1/2 Clinical Trial o...

                            Details : STX-721, Scorpion's highly differentiated, orally bioavailable, irreversible highly selective tyrosine kinase inhibitor targeting EGFR and ERBB2 (HER2) Exon 20 insertion mutations, well-known, clinically validated oncogenic drivers in non-small cell lung...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 10, 2023

                            Lead Product(s) : STX-721

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Pierre Fabre

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Scorpion Therapeutics

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                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics Announces First Patient Dosed in Phase 1/2 Clinical Trial of STX-478, Its Mutant-Selecti...

                            Details : STX-478 is a mutant-selective PI3Kα inhibitor with a potentially best-in-class profile, for the treatment of HR+/HER2- breast cancer and other solid tumors.'

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 02, 2023

                            Lead Product(s) : Tersolisib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Scorpion Therapeutics

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                            Scorpion Therapeutics

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                            Lead Product(s) : STX-721

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Pierre Fabre

                            Deal Size : $618.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics and Pierre Fabre Announce Collaboration and License Agreement to Co-Develop and Commerci...

                            Details : Under the agreement, Scorpion will lead development of STX-721 and Pierre Fabre will lead development of STX-241. Scorpion will retain commercialization rights to STX-721 and STX-241 in US, Canada and Japan, and Pierre Fabre will retain commercialization...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $65.0 million

                            April 04, 2023

                            Lead Product(s) : STX-721

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Pierre Fabre

                            Deal Size : $618.0 million

                            Deal Type : Collaboration

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                            08

                            Scorpion Therapeutics

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                            Scorpion Therapeutics

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                            Lead Product(s) : STX-241

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics Nominates STX-241 as Potentially Best-in-Class Fourth-Generation EGFR Inhibitor Developm...

                            Details : STX-241 is the second highly selective EGFR product candidate to emerge from Scorpion’s franchise of next-generation mutant EGFR inhibitors for the treatment of NSCLC.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 03, 2023

                            Lead Product(s) : STX-241

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Scorpion Therapeutics

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                            Scorpion Therapeutics

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                            Lead Product(s) : Tersolisib

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics Presents Preclinical Data for Potential Best-in-Class PI3Kα Inhibitor at San Antonio Br...

                            Details : In these studies, STX-478 showed robust anti-tumor activity as both a monotherapy and in combination with standard of care agents in models with kinase or helical domain mutations.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 08, 2022

                            Lead Product(s) : Tersolisib

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Scorpion Therapeutics

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                            Lead Product(s) : Tersolisib

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scorpion Therapeutics to Present Preclinical Data for Potential Best-in-Class Mutant-Selective PI3Kα Inhibito...

                            Details : STX-478 is a highly selective, allosteric and CNS-penetrant inhibitor of mutant PI3Kα, designed to improve outcomes in patients harboring tumors with prevalent PI3Kα kinase or helical domain mutations.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 21, 2022

                            Lead Product(s) : Tersolisib

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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