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Agreement","leadProduct":"Tisolagiline","moa":"Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Phase II","graph3":"Scilex Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Scilex Pharmaceuticals \/ Scilex Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"Scilex Pharmaceuticals \/ Scilex Pharmaceuticals"},{"orgOrder":0,"company":"Scilex Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Tisolagiline","moa":"Undisclosed","graph1":"Neurology","graph2":"Phase II","graph3":"Scilex Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Scilex Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Scilex Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Scilex Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Tisolagiline","moa":"Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Phase II","graph3":"Scilex Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Scilex Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Scilex Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Scilex Pharmaceuticals","sponsor":"IPMC","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Partnership","leadProduct":"Tisolagiline","moa":"Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Phase II","graph3":"Scilex Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Scilex Pharmaceuticals \/ IPMC","highestDevelopmentStatusID":"8","companyTruncated":"Scilex Pharmaceuticals \/ IPMC"}]

Find Clinical Drug Pipeline Developments & Deals by Scilex Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Gloperba (colchicine) disrupts the polymerization of β-tubulin into microtubules, thereby preventing the activation, degranulation & migration of neutrophils to sites of inflammation in pericarditis.

                          Product Name : Gloperba

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          April 16, 2025

                          Lead Product(s) : Colchicine

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Elyxyb, a rapid onset and ready-to-use formulation of Celecoxib, delivers a first line non-opioid therapeutic. It is indicated for migraine disorders.

                          Product Name : Elyxyb

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 15, 2025

                          Lead Product(s) : Celecoxib

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Elyxyb, a rapid onset and ready-to-use formulation of Celecoxib, delivers a first line non-opioid therapeutic. It is being evaluated for the treatment of acute pain.

                          Product Name : Elyxyb

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : Celecoxib

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Elyxyb, a rapid onset and ready-to-use formulation of Celecoxib, delivers a first line non-opioid therapeutic. It is being evaluated for the treatment of acute pain.

                          Product Name : Elyxyb

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 21, 2025

                          Lead Product(s) : Celecoxib

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : Under the licensing agreement, Scilex will be responsible for the commercialization of Gloperba (Colchicine) only in the U.S. It is indicated for the treatment of gout flares in adults.

                          Product Name : Gloperba

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Undisclosed

                          January 16, 2025

                          Lead Product(s) : Colchicine

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Recipient : Romeg Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : The Company intends to use the net proceeds for the clinical advancement of SP-102 (dexamethasone sodium phosphate), which is being evaluated for treating Lumbosacral Radicular Pain (Sciatica).

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Undisclosed

                          December 13, 2024

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : $17.0 million

                          Deal Type : Public Offering

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                          07

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : The Company intends to use the net proceeds for the clinical advancement of SP-102 (dexamethasone sodium phosphate), which is being evaluated for treating Lumbosacral Radicular Pain (Sciatica).

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Undisclosed

                          December 12, 2024

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : $17.0 million

                          Deal Type : Public Offering

                          blank

                          08

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : KDS2010 (Tisolagiline) is a potent, selective, and reversible Monoamine oxidase B (MAO-B) inhibitor being invesigated as a novel oral tablet small molecule agent for treating Alzheimer’s Disease.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Tisolagiline

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : KDS2010 (Tisolagiline) is a potent, selective, and reversible Monoamine oxidase B (MAO-B) inhibitor being invesigated as a novel oral tablet small molecule agent for treating obesity.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 11, 2024

                          Lead Product(s) : Tisolagiline

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          The MedTech Conference
                          Not Confirmed
                          The MedTech Conference
                          Not Confirmed

                          Details : NeuroBiogen grant Scilex an exclusive worldwide license to the KDS2010 drug to develop and commercialize in metabolic diseases (including obesity and type 2 diabetes) and neurodegenerative diseases.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          December 10, 2024

                          Lead Product(s) : Tisolagiline

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase II

                          Recipient : Neurobiogen

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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