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    [{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Boehringer Ingelheim GmbH","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Private Placement","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Minerva Neurosciences","amount2":0.02,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0.02,"dosageForm":"Oral Tablet","sponsorNew":"Minerva Neurosciences \/ Boehringer Ingelheim GmbH","highestDevelopmentStatusID":"10","companyTruncated":"Minerva Neurosciences \/ Boehringer Ingelheim GmbH"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A 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Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Minerva Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Minerva Neurosciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Minerva Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A 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Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Minerva Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Minerva Neurosciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Minerva Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A 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Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Minerva Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Minerva Neurosciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Minerva Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Minerva Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Minerva Neurosciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Minerva Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Minerva Neurosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Roluperidone","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Minerva Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Minerva Neurosciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Minerva Neurosciences \/ Inapplicable"},{"orgOrder":0,"company":"Mitsubishi Tanabe Pharma","sponsor":"Bain Capital","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"JAPAN","productType":"Other Small Molecule","year":"2025","type":"Acquisition","leadProduct":"Roluperidone","moa":"5-HT2A\/sigma 2 receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Mitsubishi Tanabe Pharma","amount2":3.2999999999999998,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":3.2999999999999998,"dosageForm":"Oral Tablet, Modified Release","sponsorNew":"Mitsubishi Tanabe Pharma \/ Bain Capital","highestDevelopmentStatusID":"10","companyTruncated":"Mitsubishi Tanabe Pharma \/ Bain Capital"}]

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    Roluperidone

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                            01

                            Mitsubishi Tanabe Pharma

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                            Mitsubishi Tanabe Pharma

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Bain Capital

                            Deal Size : $3,300.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Bain Capital to Acquire Mitsubishi Tanabe Pharma Corporation

                            Details : Tanabe Pharma will continue to build on its legacy of medical innovation in internal product development including MT-210 (roluperidone), being developed for schizophrenia.

                            Product Name : MT-210

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 07, 2025

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Bain Capital

                            Deal Size : $3,300.0 million

                            Deal Type : Acquisition

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                            02

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Receives Complete Response Letter from FDA for Roluperidone NDA

                            Details : MIN-101 (roluperidone) blocks serotonin, sigma, and α-adrenergic receptors, involved in brain function regulation, and is being evaluated for treating negative symptoms in schizophrenia patients.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 27, 2024

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Announces Update on its New Drug Application (NDA) for Roluperidone for the Treatment of...

                            Details : MIN-101 (roluperidone) is an investigational drug that has been shown to block serotonin, sigma and α-adrenergic receptors that are all involved in the regulation of important brain functions, including mood, cognition, sleep, and anxiety.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 05, 2023

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Boehringer Ingelheim GmbH

                            Deal Size : $20.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Announces $20 Million in Private Placement Priced at a Premium to Market

                            Details : Minerva intends to use the net proceeds to support potential regulatory approval in the U.S., commercialization activities and market launch of MIN-101 (roluperidone), which is being developed for the treatment of negative symptoms in schizophrenia.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 28, 2023

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Boehringer Ingelheim GmbH

                            Deal Size : $20.0 million

                            Deal Type : Private Placement

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                            05

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Announces the NDA Filing for Roluperidone for the Treatment of Negative Symptoms in Schi...

                            Details : MIN-101 (roluperidone) is a compound that has been shown to block serotonin, sigma and α-adrenergic receptors that are involved in the regulation of mood, cognition, sleep and anxiety. It is being developed to treat the negative symptoms of patients wit...

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 05, 2023

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Receives Refusal to File Letter from FDA for its New Drug Application for Roluperidone f...

                            Details : Roluperidone (MIN-101) has been designed to block a specific subtype of serotonin receptor called 5-HT2A. When 5-HT2A is blocked, certain symptoms of schizophrenia, such as hallucinations, delusions, agitation and thought and movement disorders.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 17, 2022

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Submits New Drug Application to FDA for Roluperidone for the Treatment of Negative Sympt...

                            Details : The MIN-101 (roluperidone) clinical development program aims to provide effective treatment for negative symptoms of schizophrenia, a significant unmet medical need in a large patient population.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 22, 2022

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Provides Update from Type C Meeting with FDA and Next Steps in Preparation for Submissio...

                            Details : MIN-101 (roluperidone) is a compound that has been shown to block serotonin, sigma and α-adrenergic receptors that are involved in the regulation of mood, cognition, sleep and anxiety to treat negative symptoms of patients with schizophrenia.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 04, 2022

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Announces the Results of the Phase 3 Trial of Roluperidone for the Treatment of Negative...

                            Details : Roluperidone at both doses was safe and well tolerated, and treatment-emergent adverse events (TEAE) were generally mild to moderate in severity.

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 05, 2021

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Minerva Neurosciences

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                            Minerva Neurosciences

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                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minerva Neurosciences Announces Results From Phase 3 Trial of Roluperidone (MIN-101) for Treatment of Negative...

                            Details : The 64 mg and 32 mg doses were not statistically significantly different from placebo at Week 12 on the primary endpoint, the PANSS Marder Negative Symptoms Factor Score, or the key secondary endpoint, the Personal and Social Performance Scale Total Scor...

                            Product Name : MIN-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 29, 2020

                            Lead Product(s) : Roluperidone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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