Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Praxis Gains Rare Pediatric Disease Designation for Relutrigine in Dravet Syndrome
Details : PRAX-562 (relutrigine) is being evaluated in the mid-stage clinical trial for the treatment of patients suffering from SCN2A and SCN8A Encephalopathy.
Product Name : PRAX-562
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 18, 2024
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Praxis to Announce Phase 2 Data for Relutrigine in Developmental Epileptic Disorders
Details : PRAX-562 (relutrigine) is being evaluated in the mid-stage clinical trial for the treatment of patients suffering from SCN2A and SCN8A Encephalopathy.
Product Name : PRAX-562
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 09, 2024
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PRAX-562 is a first-in-class small molecule in development for the treatment of DEEs as a preferential inhibitor of persistent sodium current, shown to be a key driver of seizure symptoms in early onset SCN2A-DEE and SCN8A-DEE.
Product Name : PRAX-562
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 28, 2022
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Relutrigine
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PRAX-562 is a first selective persistent sodium current blocker. Praxis plans to initiate a Phase 2 clinical trial in the first half of 2022 to explore the potential for PRAX-562 to treat a range of rare pediatric DEEs, including SCN2A-DEE and SCN8A-DEE.
Product Name : PRAX-562
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 30, 2021
Lead Product(s) : Relutrigine
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Praxis Precision Medicines
Deal Size : Undisclosed
Deal Type : Partnership
Praxis Precision Medicines Partners With Ciitizen to Improve Patient-Guided Drug Development
Details : Praxis will utilize the Ciitizen platform to provide deeper insights across disease populations through the analysis of real-world data, initially to inform the development of PRAX-222 and PRAX-562 in SCN2A developmental and epileptic encephalopathy (SCN...
Product Name : PRAX-562
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 16, 2021
Lead Product(s) : Relutrigine
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Praxis Precision Medicines
Deal Size : Undisclosed
Deal Type : Partnership