
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

RLY-2608+Fulvestrant vs Capivasertib+Fulvestrant Efficacy in PIK3CA-mutant Breast Cancer
Details : RLY-2608 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Breast Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 21, 2025

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Lead Product(s) : RLY-2608
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RLY-2608 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of PIK3CA-mutated Overgrowth Spectrum.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 23, 2025
Lead Product(s) : RLY-2608
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : RLY-2608,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Relay Announces Updated Data for RLY-2608 + Fulvestrant in Progression-Free Survival
Details : RLY-2608 is a PI3K alpha inhibitor, small molecule, which is being evaluated for the treatment of patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 11, 2024
Lead Product(s) : RLY-2608,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : RLY-4008
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Elevar Therapeutics
Deal Size : $500.0 million
Deal Type : Licensing Agreement
Elevar & Relay Therapeutics License Lirafugratinib for FGFR2 Cancer & Solid Tumors
Details : The agreement grants Elevar worldwide rights to develop and commercialize RLY-4008 (lirafugratinib), an oral small molecule inhibitor of FGFR2 being developed for FGFR2-driven cholangiocarcinoma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $75.0 million
December 03, 2024
Lead Product(s) : RLY-4008
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Elevar Therapeutics
Deal Size : $500.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : RLY-4008
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Goldman Sachs & Co
Deal Size : $200.0 million
Deal Type : Public Offering
Relay Therapeutics Announces Pricing of Public Offering of Common Stock
Details : The net proceeds from the offering will be used for research & development of the Company’s lead product, including RLY-4008 for the treatment of FGFR2-mutated Cholangiocarcinoma and other neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 10, 2024
Lead Product(s) : RLY-4008
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Goldman Sachs & Co
Deal Size : $200.0 million
Deal Type : Public Offering

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Lead Product(s) : RLY-4008
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Goldman Sachs & Co
Deal Size : $200.0 million
Deal Type : Public Offering
Relay Therapeutics Announces Proposed Public Offering of Common Stock
Details : The net proceeds from the offering will be used for research & development of the Company’s lead product, including RLY-4008 for the treatment of FGFR2-mutated Cholangiocarcinoma and other neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 09, 2024
Lead Product(s) : RLY-4008
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Goldman Sachs & Co
Deal Size : $200.0 million
Deal Type : Public Offering

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Lead Product(s) : RLY-2608,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Relay Therapeutics Announces Positive Interim Data for RLY-2608 in Cancer Treatment
Details : RLY-2608 is a PI3K alpha inhibitor, small molecule, which is being evaluated for the treatment of patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 09, 2024
Lead Product(s) : RLY-2608,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : RLY-2608,Atirmociclib,Fulvestrant
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Pfizer Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Relay Therapeutics, Pfizer to Collaborate on Atirmociclib and RLY-2608 Clinical Trial
Details : The collaboration with Pfizer to evaluate atirmociclib, selective-CDK4 inhibitor, in combination with RLY-2608 and fulvestrant in patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 05, 2024
Lead Product(s) : RLY-2608,Atirmociclib,Fulvestrant
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Pfizer Inc
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : RLY-2608,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Nextech
Deal Size : $30.0 million
Deal Type : Private Placement
Relay Therapeutics Announces $30 Million Private Placement Financing
Details : Relay Therapeutics expects to use net proceeds to advance RLY-2608, , a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 08, 2024
Lead Product(s) : RLY-2608,Fulvestrant,Palbociclib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Nextech
Deal Size : $30.0 million
Deal Type : Private Placement

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Recipient : X-Chem
Deal Size : Undisclosed
Deal Type : Collaboration
X-Chem Announces Achievement of Collaboration Milestone
Details : Under the collaboration, Relay Therapeutics utilized X-Chem’s DNA-Encoded Library platform to perform hit finding intended to discover molecules with differentiated pharmacological properties.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 05, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Recipient : X-Chem
Deal Size : Undisclosed
Deal Type : Collaboration
