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Tyrosine-protein kinase ABL | Stem cell growth factor receptor | Vascular endothelial growth factor receptor | Fibroblast growth factor receptor 1 | Serine\/threonine-protein kinase RAF | Platelet-derived growth factor receptor | Tyrosine-protein kinase receptor RET | Discoidin domain-containing receptor 2 | Ephrin type-A receptor 2 | Tyrosine-protein kinase TIE-2","graph1":"Oncology","graph2":"Phase III","graph3":"Bayer AG","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Bayer AG \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Bayer AG \/ Inapplicable"},{"orgOrder":0,"company":"Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center","sponsor":"Qilu Pharmaceutical | Shanghai Junshi Biomedical Technology Co., Ltd","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Regorafenib","moa":"Serine\/threonine-protein kinase B-raf | Nerve growth factor receptor Trk-A | Tyrosine-protein kinase FRK | Fibroblast growth factor receptor 2 | MAP kinase p38 beta | Tyrosine-protein kinase ABL | Stem cell growth factor receptor | Vascular endothelial gr","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center \/ Qilu Pharmaceutical | Shanghai Junshi Biomedical Technology Co., Ltd","highestDevelopmentStatusID":"7","companyTruncated":"Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center \/ Qilu Pharmaceutical | Shanghai Junshi Biomedical Technology Co., Ltd"},{"orgOrder":0,"company":"MD Anderson Cancer Center","sponsor":"Bayer AG | MacroGenics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Regorafenib","moa":"Serine\/threonine-protein kinase B-raf | Nerve growth factor receptor Trk-A | Tyrosine-protein kinase FRK | Fibroblast growth factor receptor 2 | MAP kinase p38 beta | Tyrosine-protein kinase ABL | Stem cell growth factor receptor | Vascular endothelial gr","graph1":"Oncology","graph2":"Phase II","graph3":"MD Anderson Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"MD Anderson Cancer Center \/ Bayer AG | MacroGenics","highestDevelopmentStatusID":"8","companyTruncated":"MD Anderson Cancer Center \/ Bayer AG | MacroGenics"}]

Find Clinical Drug Pipeline Developments & Deals for Regorafenib

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                          Top Deals by Deal Size (USD bn)

                          01

                          MD Anderson Cancer Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          MD Anderson Cancer Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Regorafenib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Colorectal Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 18, 2025

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bayer AG | MacroGenics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          02

                          Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Qilu Pharmaceutical | Shanghai Junshi Biomedical Technology Co., Ltd

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Regorafenib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Pancreatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 27, 2025

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Qilu Pharmaceutical | Shanghai Junshi Biomedical Technology Co., Ltd

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          University of Miami

                          Country arrow
                          ESCRS
                          Not Confirmed

                          University of Miami

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 30, 2025

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Centre Hospitalier Universitaire de Besancon

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Centre Hospitalier Universitaire de Besancon

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Study Phase : Phase II

                          Sponsor : Groupement Interrégional de Recherche Clinique et d'Innovation

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 22, 2024

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Groupement Interrégional de Recherche Clinique et d'Innovation

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : PRO-140 (leronlimab) a monoclonal antibody works by blocking the activity of the CCR5 receptor, being developed in combination with Regorafenib for MSS mCRC.

                          Product Name : Vyrologix

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 11, 2024

                          Lead Product(s) : Leronlimab,Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          06

                          Istituto Oncologico Veneto

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Istituto Oncologico Veneto

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 23, 2024

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 07, 2024

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          MD Anderson Cancer Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          MD Anderson Cancer Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 17, 2023

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Ibrahim Halil Sahin

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Ibrahim Halil Sahin

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 23, 2023

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          MD Anderson Cancer Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          MD Anderson Cancer Center

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 12, 2023

                          Lead Product(s) : Regorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Xencor | Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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