
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : California Institute for Regenerative Medicine
Deal Size : $8.0 million
Deal Type : Funding
Ray Therapeutics gets $8M CIRM Grant for Retinitis Pigmentosa Gene Therapy
Details : The grant will support the company’s ongoing development of RTx-015 for the treatment of retinitis pigmentosa, a progressive and debilitating inherited retinal disease that leads to blindness.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
April 24, 2025
Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : California Institute for Regenerative Medicine
Deal Size : $8.0 million
Deal Type : Funding

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Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RTx-015 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Retinitis Pigmentosa.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 14, 2024
Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : RTx-021
Therapeutic Area : Ophthalmology
Study Phase : Discovery
Sponsor : Cirm
Deal Size : $4.0 million
Deal Type : Funding
Details : The funding will be used to support development of RTx-021, an optogenetic therapy for the treatment of geographic atrophy (GA), the advanced form of age-related macular degeneration (AMD).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
November 13, 2023
Lead Product(s) : RTx-021
Therapeutic Area : Ophthalmology
Highest Development Status : Discovery
Sponsor : Cirm
Deal Size : $4.0 million
Deal Type : Funding

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Lead Product(s) : RTx-015,AAV.7m8
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Recipient : Adverum Biotechnologies
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Adverum Biotechnologies Grants License to Ray Therapeutics Inc. for the AAV.7m8 Intravitreal Capsid
Details : Under the agreement, Adverum grants Ray Therapeutics a worldwide, non-exclusive license of AAV.7m8 together with its RTx-015 asset, for the prevention, treatment, diagnosis or amelioration of any ocular disorder utilizing Ray’s optogenetics approach.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
June 12, 2023
Lead Product(s) : RTx-015,AAV.7m8
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Recipient : Adverum Biotechnologies
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Novo Holding
Deal Size : $100.0 million
Deal Type : Series A Financing
Details : The financing will advance Ray Therapeutics’ optogenetics gene therapy programs for blinding retinal diseases including, RTx-015, a genotype agnostic, intended for use in treating patients with retinitis pigmentosa (RP).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
May 16, 2023
Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Novo Holding
Deal Size : $100.0 million
Deal Type : Series A Financing

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Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Forge Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Forge will provide research-grade and GMP-Pathway plasmid manufacturing services, in addition to adeno-associated viral vector (AAV) process development, scale-up engineering, and cGMP manufacturing services for Ray Therapeutics’ program, RTx-015.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
October 10, 2022
Lead Product(s) : RTx-015
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Forge Biologics
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Ray-001
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : California Institute for Regenerative Medicine
Deal Size : $4.0 million
Deal Type : Funding
Details : Funding will advance development of Ray Therapeutics’ optogenetics technology platform – Ray-001 for the treatment of Retinitis Pigmentosa. In preclinical studies, RAY-001 is intended to be a one-time treatment via intravitreal injection that is sust...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
April 26, 2022
Lead Product(s) : Ray-001
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : California Institute for Regenerative Medicine
Deal Size : $4.0 million
Deal Type : Funding

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Lead Product(s) : Ray-001
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Forge Biologics
Deal Size : Undisclosed
Deal Type : Partnership
Details : Ray-001 is intended for use in treating patients with retinitis pigmentosa (RP). Optogenetics is a promising approach that has the potential to restore useful vision to visually-impaired and blind individuals.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
March 01, 2022
Lead Product(s) : Ray-001
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Forge Biologics
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Ray-001
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : 4BIO Capital
Deal Size : $6.0 million
Deal Type : Financing
Details : The funding will be used to advance its optogenetic therapy, Ray-001, into clinical trials in retinitis pigmentosa (RP). Based on the durability of treatment demonstrated in preclinical studies, Ray-001 is intended to be a one-time treatment via intravit...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
January 04, 2022
Lead Product(s) : Ray-001
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : 4BIO Capital
Deal Size : $6.0 million
Deal Type : Financing
