
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : RPT904
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RPT904 is a Antibody, Unconjugated drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Food Hypersensitivity.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 29, 2025
Lead Product(s) : RPT904
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tivumecirnon,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : The Column Group
Deal Size : $150.0 million
Deal Type : Private Placement
RAPT Therapeutics Announces $150 Million Private Placement
Details : The net proceeds from the private placement will support the research and development of the company’s pipeline, including FLX475 (tivumecirnon) in combination with Keytruda for treating NSCLC.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 23, 2024
Lead Product(s) : Tivumecirnon,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : The Column Group
Deal Size : $150.0 million
Deal Type : Private Placement

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Lead Product(s) : JYB1904
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Recipient : Jemincare
Deal Size : $707.5 million
Deal Type : Licensing Agreement
RAPT, Jemincare License Novel Anti-IgE Antibody With Long-Acting Therapeutic Effects
Details : The agreement aims for JYB1904/RPT904, a novel, half-life extended anti-IgE mAb for the treatment food allergies, chronic spontaneous urticaria and other allergic inflammatory diseases.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : $35.0 million
December 23, 2024
Lead Product(s) : JYB1904
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Recipient : Jemincare
Deal Size : $707.5 million
Deal Type : Licensing Agreement

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Lead Product(s) : Zelnecirnon
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RAPT Therapeutics Stops Zelnecirnon Program After Clinical Hold
Details : RPT193 (zelnecirnon) is an antagonist of CCR4 receptor that inhibits CCR4-mediated chemotaxis toward both CCL22 and CCL17. It was being evaluated for the treatment of atopic dermatitis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 11, 2024
Lead Product(s) : Zelnecirnon
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tivumecirnon,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RAPT Announces Phase 2 Trial Result of Tivumecirnon with Anti-PD-1 in Head and Neck Cancer
Details : FLX475 (tivumecirnon) is a small molecule CCR4 antagonist, is being evaluated with Pembrolizumab for the treatment of advanced head and neck squamous cell carcinoma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 09, 2024
Lead Product(s) : Tivumecirnon,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Zelnecirnon
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
RAPT Therapeutics Announces Clinical Hold on Studies Evaluating Zelnecirnon
Details : RPT193 (zelnecirnon) is an antagonist of CCR4 receptor that inhibits CCR4-mediated chemotaxis toward both CCL22 and CCL17. It is being evaluated for the treatment of atopic dermatitis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 20, 2024
Lead Product(s) : Zelnecirnon
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tivumecirnon,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : FLX475 (tivumecirnon), an oral small molecule CCR4 antagonist designed to block the migration of regulatory T cells, in combination with the checkpoint inhibitor pembrolizumab for pateint with NSCLC.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 03, 2023
Lead Product(s) : Tivumecirnon,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Zelnecirnon
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of RPT193 in Healthy Adult Male Subjects
Details : RPT193 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 18, 2023
Lead Product(s) : Zelnecirnon
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Zelnecirnon
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma
Details : RPT193 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Asthma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 07, 2023
Lead Product(s) : Zelnecirnon
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Zelnecirnon
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RPT193 is a small molecule, CCR4 antagonist designed to selectively inhibit the migration of Th2 cells into inflamed tissues In allergic inflammatory diseases such as atopic dermatitis and asthma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 29, 2023
Lead Product(s) : Zelnecirnon
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
