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Nantahala Capital","highestDevelopmentStatusID":"10","companyTruncated":"Quince Therapeutics \/ Nantahala Capital"},{"orgOrder":0,"company":"Quince Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"COR588","moa":"Lysine gingipain","graph1":"Undisclosed","graph2":"Phase I","graph3":"Quince Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Quince Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Quince Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Quince Therapeutics","sponsor":"Lighthouse Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Divestment","leadProduct":"COR588","moa":"Lysine 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Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Quince Therapeutics \/ Inapplicable"}]

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                          01

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : The proceeds from placement will be used to fund the clinical development of late-stage Erydex (dexamethasone sodium phosphate), which is being evaluated for the treatment of Ataxia Telangiectasia.

                          Product Name : Erydex

                          Product Type : Steroid

                          Upfront Cash : $10.4 million

                          June 12, 2025

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Nantahala Capital

                          Deal Size : $21.9 million

                          Deal Type : Private Placement

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                          02

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          October 30, 2024

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Biotrial

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : EryDex (dexamethasone sodium phosphate) is a glucocorticoid receptor agonist, which is being evaluated in the late-stage clinical trial studies for the treatment of Ataxia-Telangiectasia.

                          Product Name : EryDex

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          June 25, 2024

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : EryDex (dexamethasone sodium phosphate), utilizing company's AIDE technology, is in Phase 3 for treating Ataxia-Telangiectasia, a rare pediatric condition.

                          Product Name : EryDex

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          March 06, 2024

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          January 05, 2024

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Biotrial

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Through the acquisition, Quince gains right for EryDel's Phase 3 lead asset, EryDex (dexamethasone sodium phosphate), targeting a rare fatal pediatric neurological disease, Ataxia-Telangiectasia (A-T), which currently has no approved treatments.

                          Product Name : EryDex

                          Product Type : Steroid

                          Upfront Cash : $485.0 million

                          October 23, 2023

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Recipient : EryDel

                          Deal Size : $485.0 million

                          Deal Type : Acquisition

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                          07

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : EryDex (dexamethasone sodium phosphate) utilizes a unique drug/device combination that enables a fully automated process at the point of patient care for the autologous intracellular drug encapsulation for the Treatment of Ataxia-Telangiectasia.

                          Product Name : EryDex

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          September 28, 2023

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Through the acquisition, Quince gains right for EryDel's Phase 3 lead asset, EryDex (dexamethasone sodium phosphate), targeting a rare fatal pediatric neurological disease, Ataxia-Telangiectasia (A-T), which currently has no approved treatments.

                          Product Name : EryDex

                          Product Type : Steroid

                          Upfront Cash : $485.0 million

                          July 24, 2023

                          Lead Product(s) : Dexamethasone Sodium Phosphate

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Recipient : EryDel

                          Deal Size : $485.0 million

                          Deal Type : Acquisition

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                          09

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Under the agreement, Lighthouse gains exclusive rights to develop, manufacture, and commercialize Quince’s legacy protease inhibitor portfolio including, COR588, COR388, COR852, and COR803 globally.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 30, 2023

                          Lead Product(s) : COR588

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Recipient : Lighthouse Pharmaceuticals

                          Deal Size : $150.0 million

                          Deal Type : Divestment

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                          10

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : In preclinical studies, NOV004 concentrated at spinal fusion sites to demonstrate accelerated repair in treated animals which resulted in improved blinded radiographic fusion scores compared to animals treated with current standard of care, bone morphoge...

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          December 09, 2022

                          Lead Product(s) : NOV004

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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