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    [{"orgOrder":0,"company":"Qpex Biopharma","sponsor":"Shionogi | Biomedical Advanced Research and Development Authority","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Xeruborbactam Prodrug","moa":"Bacterial beta-lactamase","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Qpex Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Qpex Biopharma \/ Shionogi | Biomedical Advanced Research and Development Authority","highestDevelopmentStatusID":"6","companyTruncated":"Qpex Biopharma \/ Shionogi | Biomedical Advanced Research and Development Authority"},{"orgOrder":0,"company":"Qpex Biopharma","sponsor":"Shionogi | Biomedical Advanced Research and Development 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Biopharma","highestDevelopmentStatusID":"6","companyTruncated":"Qpex Biopharma \/ Qpex Biopharma"},{"orgOrder":0,"company":"Qpex Biopharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibiotic","year":"2022","type":"Inapplicable","leadProduct":"QPX9003","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Qpex Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Qpex Biopharma \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Qpex Biopharma \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals by Qpex Biopharma

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                            01

                            Qpex Biopharma

                            U.S.A arrow
                            BOS Manchester
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                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : Cefiderocol

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety and Pharmacokinetics of IV Cefiderocol/Xeruborbactam In Renal Impairment

                            Details : Cefiderocol is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Bacterial Infections.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 05, 2025

                            Lead Product(s) : Cefiderocol

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Qpex Biopharma

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                            BOS Manchester
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                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : 14-C Xeruborbactam

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Shionogi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Mass Balance Study of [14C]Xeruborbactam (QPX7728) in Healthy Adult Male Participants

                            Details : 14-C Xeruborbactam is a Radiolabelled Compounds drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.

                            Product Name : Undisclosed

                            Product Type : Radiolabeled Compound

                            Upfront Cash : Inapplicable

                            July 24, 2025

                            Lead Product(s) : 14-C Xeruborbactam

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Shionogi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Qpex Biopharma

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                            BOS Manchester
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                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : Xeruborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Par...

                            Details : Xeruborbactam is a Antibiotic drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Bacterial Infections.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            August 09, 2024

                            Lead Product(s) : Xeruborbactam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Qpex Biopharma

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                            BOS Manchester
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                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : Xeruborbactam Prodrug

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

                            Details : Xeruborbactam Prodrug is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Bacterial Infections.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            December 05, 2023

                            Lead Product(s) : Xeruborbactam Prodrug

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Qpex Biopharma

                            U.S.A arrow
                            BOS Manchester
                            Not Confirmed

                            Qpex Biopharma

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                            BOS Manchester
                            Not Confirmed
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                            Lead Product(s) : Xeruborbactam Prodrug

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participan...

                            Details : Xeruborbactam Prodrug is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Bacterial Infections.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            October 12, 2023

                            Lead Product(s) : Xeruborbactam Prodrug

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Shionogi | Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Qpex Biopharma

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                            BOS Manchester
                            Not Confirmed

                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : Xeruborbactam,QPX2015

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Shionogi

                            Deal Size : $140.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Shionogi Further Extends Infectious Disease Innovation Platform with Planned Acquisition of Qpex Biopharma, In...

                            Details : Through the acquisition, Shionogi extends its infectious disease innovation platform with the access to a novel investigational beta-lactamase inhibitor, QPX7728 (xeruborbactam), which is being advanced clinically for infections caused by drug-resistant ...

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : $100.0 million

                            June 25, 2023

                            Lead Product(s) : Xeruborbactam,QPX2015

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Shionogi

                            Deal Size : $140.0 million

                            Deal Type : Acquisition

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                            07

                            Qpex Biopharma

                            U.S.A arrow
                            BOS Manchester
                            Not Confirmed

                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : QPX9003

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : Brii Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Brii Biosciences Announces Entry into Definitive Agreements from Sale of its Equity Interest in Qpex Biopharma...

                            Details : Brii Bio will acquire exclusive global rights for the development and commercialization of QPX9003 (BRII-693), a novel synthetic lipopeptide in development for the treatment of MDR/XDR gram-negative bacterial infections, to expand from its existing right...

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : $24.0 million

                            June 25, 2023

                            Lead Product(s) : QPX9003

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : Brii Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            08

                            Qpex Biopharma

                            U.S.A arrow
                            BOS Manchester
                            Not Confirmed

                            Qpex Biopharma

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                            BOS Manchester
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                            Lead Product(s) : Xeruborbactam,Meropenem

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Qpex Biopharma Announces Presentations on Phase 1 and Nonclinical Data on Three Clinical Stage Oral and IV Pro...

                            Details : ORAvance (Xeruborbactam) an orally-administered combination product that delivers xeruborbactam to treat infections that occur in outpatient and community setting caused by drug-resistant gram-negative bacteria.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            October 17, 2022

                            Lead Product(s) : Xeruborbactam,Meropenem

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Qpex Biopharma

                            U.S.A arrow
                            BOS Manchester
                            Not Confirmed

                            Qpex Biopharma

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                            BOS Manchester
                            Not Confirmed
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                            Lead Product(s) : Xeruborbactam,QPX2014

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Qpex Biopharma Announces Presentation of Clinical Data for Ultra-Broad Spectrum β-lactamase Inhibitor Xerubor...

                            Details : New clinical data for β-lactamase inhibitor xeruborbactam (formerly QPX7728) and synthetic lipopeptide QPX9003, represent new potential therapies for patients with drug-resistant infections – notably carbapenem-resistant Acinetobacter, Pseudomonas, an...

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            April 21, 2022

                            Lead Product(s) : Xeruborbactam,QPX2014

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Qpex Biopharma

                            U.S.A arrow
                            BOS Manchester
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                            Qpex Biopharma

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                            BOS Manchester
                            Not Confirmed
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                            Lead Product(s) : QPX9003

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Qpex Biopharma Announces Publication of Data in Nature Communications on the New Synthetic Lipopeptide Antibio...

                            Details : The resulting new lipopeptide QPX9003 is pharmacologically distinct from existing polymyxin drugs with a superior safety and efficacy against experimentally-induced lung infections caused by Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella ...

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            March 30, 2022

                            Lead Product(s) : QPX9003

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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