
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Q32 Bio's Bempikibart gets FDA Fast Track for Treating Alopecia Areata
Details : ADX-914 (bempikibart) is a fully human anti-IL-7R alpha antibody, being investigated for the treatment of alopecia areata.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 30, 2025
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Q32 Doses First Patients in SIGNAL-AA Trial for Alopecia Areata
Details : ADX-914 (bempikibart) is a dual inhibitor of IL-7 and TSLP signaling, being investigated for the treatment of alopecia areata.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 16, 2025
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Q32 Bio Updates Bempikibart Program for Alopecia Areata Development
Details : ADX-914 (bempikibart), is a fully human anti-IL-7Rα antibody, which is currently being developed for the treatment of patients with alopecia areata.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Q32 Bio Completes Enrollment in Phase 2 Trial of Bempikibart for Atopic Dermatitis
Details : ADX-914 (bempikibart), is a fully human anti-IL-7Rα antibody, being developed in a Phase 2 trial for the treatment of atopic dermatitis (AD).
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 09, 2024
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ADX-097
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADX-097 is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Glomerulonephritis, IGA.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
May 17, 2024
Lead Product(s) : ADX-097
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Recipient : Homology Medicines
Deal Size : Undisclosed
Deal Type : Merger
Q32 Bio Closes Merger with Homology Medicines and Raises $42 Million
Details : The combined company will develop Q32 Bio’s clinical candidates, ADX-914 for atopic dermatitis and alopecia areata, and ADX-097 for complement disorders, both in Phase 2.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
March 25, 2024
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Recipient : Homology Medicines
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : OrbiMed Advisors
Deal Size : $42.0 million
Deal Type : Private Placement
Q32 Bio Closes Merger with Homology Medicines and Raises $42 Million
Details : Proceeds will advance the clinical development of Q32 Bio’s assets: ADX-914 (bempikibart) in Phase 2 for atopic dermatitis and ADX-097 in Phase 2 for complement disorders.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
March 25, 2024
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : OrbiMed Advisors
Deal Size : $42.0 million
Deal Type : Private Placement

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Recipient : Homology Medicines
Deal Size : Undisclosed
Deal Type : Merger
Q32 Bio and Homology Medicines Announce Merger Agreement
Details : The combined company will advance the development of Q32 Bio’s two clinical development candidates, ADX-914 (bempikibart) in Phase 2 for the treatment of atopic dermatitis (AD) and alopecia areata (AA), and ADX-097 entering Phase 2 for the treatment of...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
November 16, 2023
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Recipient : Homology Medicines
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : OrbiMed Advisors
Deal Size : $42.0 million
Deal Type : Private Placement
Q32 Bio and Homology Medicines Announce Merger Agreement
Details : The proceeds will be used to advance the clinical development of Q32 Bio’s two wholly owned assets, ADX-914 (bempikibart), in Phase 2 for the treatment of atopic dermatitis (AD) and alopecia areata (AA), and ADX-097 entering Phase 2 for the treatment o...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
November 16, 2023
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : OrbiMed Advisors
Deal Size : $42.0 million
Deal Type : Private Placement

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Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Amgen Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADX-914 (bempikibart) is a fully human anti-IL-7R alpha antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and TSLP, which is investigated for the treatment of severe alopecia areata.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 13, 2023
Lead Product(s) : Bempikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Amgen Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
