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Lead Product(s): Vafidemstat
Therapeutic Area: Psychiatry/Psychology Product Name: ORY-2001
Highest Development Status: Phase II Product Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 29, 2021
Details:
PORTICO is a multicenter, double-blind, randomized, placebo-controlled Phase IIb trial to evaluate the efficacy and safety of vafidemstat in BPD patients. Oryzon’s LSD1 program has rendered two compounds, vafidemstat and iadademstat, in Phase II clinical trials.
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Lead Product(s): Vafidemstat
Therapeutic Area: Psychiatry/Psychology Product Name: ORY-2001
Highest Development Status: Phase II Product Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 24, 2021
Details:
In the trial, vafidemstat was well tolerated and did not produce any severe adverse events (SAEs) in either the Single Ascending Dose or Multiple Ascending Dose parts.
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Lead Product(s): Vafidemstat
Therapeutic Area: Psychiatry/Psychology Product Name: ORY-2001
Highest Development Status: Phase II Product Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 10, 2020
Details:
PORTICO is a multicenter, double-blind, randomized, placebo-controlled Phase IIb trial to evaluate the efficacy and safety of vafidemstat in BPD patients with agitation/aggressiveness.
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