Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GT0918 (pruxelutamide), an oral therapeutic drug, independently has been showing to accelerate viral clearance and recovery rate in COVID-19 patients by blocking SARS-CoV-2 infiltrating into host cells though down-regulating ACE2 and TMPRSS2 expressions.
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 17, 2022
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Prokalutamide can effectively reduce the hospitalization/mortality rate of new crown patients, especially for all patients who took the drug for more than 7 days, the corresponding protection rate reached 100%.
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 04, 2022
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Proxalutamide, an ACE2 (angiotensin-converting enzyme 2) and TMPRSS2 (transmembrane protease, serine 2) proteins inhibitor demonstrates a significant reduction in hospitalization/death rate with a protection rate reaching 100% for patients treated more t...
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 04, 2022
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Statistical criteria were not met at an interim analysis of the phase III outpatient study, designed for testing efficacy and safety of proxalutamide, a silent antagonist of the androgen receptor for treating COVID-19 in non-hospitalized COVID-19 patient...
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 27, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Kintor’s Preliminary Result of COVID-19 Trial in Female Patients
Details : According to the latest data from the trial, the percentage of hospitalisation, ICU admission, and the need for mechanical ventilation and death was at 1.7% versus 17.1%, 0% versus 8.6%, 0% versus 5.7% and 0% versus 2.9% in the Proxalutamide and placebo ...
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 01, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The percentage of hospitalization, admission to ICU, mechanical ventilation requirement and death was 1.7% vs. 17.1%, 0% vs. 8.6%, 0% vs. 5.7% and 0%, vs. 2.9% in Proxalutamide and placebo arms respectively.
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 01, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A nonsteroidal antiandrogen, proxalutamide is a selective high-affinity silent antagonist of the androgen receptor being developed for treating Covid-19, prostate cancer, and breast cancer.
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 26, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In addition, proxalutamide has demonstrated potential benefits in 7 of the patients who initially required high flow oxygen.
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 16, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Fosun Pharmaceutical
Deal Size : $86.6 million
Deal Type : Collaboration
Details : Proxalutamide is a new-generation androgen receptor (AR) antagonist. Since the outbreak of the COVID-19 pandemic in early 2020, Kintor Pharmaceutical has made rapid progress on the study on proxalutamide as a potential treatment for COVID-19 indication.
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 15, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Fosun Pharmaceutical
Deal Size : $86.6 million
Deal Type : Collaboration
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Applied Biology
Deal Size : Inapplicable
Deal Type : Inapplicable
Proxalutamide Phase III Clinical Trial for the Treatment of COVID-19 Patients Approved by FDA
Details : Kintor Pharmaceutical's Investigational New Drug (IND) application of the phase III clinical trial of Proxalutamide's treatment of male COVID-19 outpatients has been approved by the United States Food and Drug Administration (FDA).
Product Name : GT0918
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 03, 2021
Lead Product(s) : Proxalutamide
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Applied Biology
Deal Size : Inapplicable
Deal Type : Inapplicable