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    [{"orgOrder":0,"company":"Primmune Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"PRTX007","moa":"Toll-like-7 receptor","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"Primmune Therapeutics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Primmune Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Primmune Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Primmune Therapeutics","sponsor":"Defense Threat Reduction Agency","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Funding","leadProduct":"PRTX007","moa":"Toll-like-7 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    Find Clinical Drug Pipeline Developments & Deals by Primmune Therapeutics

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                            01

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Defense Threat Reduction Agency

                            Deal Size : $22.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Primmune Secures $22.5M Contract from DTRA to Advance PRTX007 for Lassa Fever Treatment

                            Details : The net proceeds will be used to develop PRTX007, a clinical-stage novel oral small molecule, as an oral broad spectrum antiviral TLR7 agonist for the treatment of Lassa fever.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 20, 2024

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Defense Threat Reduction Agency

                            Deal Size : $22.5 million

                            Deal Type : Funding

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                            02

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Primmune Therapeutics to Present Clinical Data from Phase 1 Study Evaluating PRTX007 at the Conference on Retr...

                            Details : PRTX007 is designed to provide immediate benefit to patients through controlled stimulation of the innate immune response while also potentiating long-term effective innate and adaptive immune responses.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 02, 2022

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Primmune Therapeutics to Present Interim Clinical Data from Phase 1 Study Evaluating PRTX007 at the 2022 Ameri...

                            Details : PRTX007 is Primmune’s lead clinical development candidate that is designed to provide well tolerated, controlled, long-term stimulation of the innate immune response while also potentiating long-term effective innate and adaptive immune responses.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 28, 2022

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Primmune Therapeutics

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                            Excipient World
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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Primmune Therapeutics Presents Data Evaluating PRTX007 as an Antiviral at the 35th International Conference on...

                            Details : Findings demonstrate broad-spectrum antiviral activity and suitability of PRTX007, also exhibits activation of the innate immune system in both cellular and murine animal models against respiratory syncytial virus (RSV).

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 21, 2022

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Primmune Therapeutics Presents Interim Analysis of Clinical Data from Phase 1 Study Evaluating PRTX007 at the ...

                            Details : Oral administration of PRTX007 in this first-in-human study of healthy volunteers exhibited a favorable safety profile, rapid absorption and conversion to TLR7 agonist PRX034, and activation of the innate immune system, without causing inflammation.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 14, 2022

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $8.4 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Primmune Therapeutics Receives $8.4 Million in Second Tranche of Series A Financing

                            Details : The fund will be used to support the further clinical development of PRTX007 as a TherAjuvant™ for acute viral diseases, pre-cancerous lesions, and advanced cancer. PRTX007 is a novel orally-administered, small molecule toll-like receptor 7 (TLR7) agon...

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            April 11, 2021

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $8.4 million

                            Deal Type : Series A Financing

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                            07

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Primmune Therapeutics Provides Update on Phase 1 Healthy Volunteer Study of PRTX007, A First in Class Novel Or...

                            Details : PRTX007 is Primmune’s lead TherAjuvant™ small molecule toll-like receptor 7 (TLR7) specific agonist for acute viral diseases, including SARS-CoV-2, and cancer.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 11, 2021

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Cam Capital

                            Deal Size : $27.4 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Primmune Therapeutics Announces $27.4 Million Series A Financing

                            Details : This financing will enable the company to move PRTX007 into a short-term pharmacokinetic, pharmacodynamic and tolerability study in humans to be followed by a clinical proof-of-concept study in an acute viral disease setting.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 27, 2020

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Cam Capital

                            Deal Size : $27.4 million

                            Deal Type : Series A Financing

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                            09

                            Primmune Therapeutics

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                            Primmune Therapeutics

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                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Primmune Therapeutics Announces the Selection of PRTX007 for COVID-19 and Oncology Indications

                            Details : PRTX007 derived from Primmune's extensive TLR7 agonist discovery program, has demonstrated sustained dose-dependent innate immune induction in vivo without the production of inflammatory cytokines.

                            Product Name : PRTX007

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 31, 2020

                            Lead Product(s) : PRTX007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Undisclosed

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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