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Corporation","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2014","type":"Inapplicable","leadProduct":"Pomalidomide","moa":"CRL4(CRBN) E3 ubiquitin ligase","graph1":"Oncology","graph2":"Phase II","graph3":"ONCOtherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ONCOtherapeutics \/ Celgene Corporation","highestDevelopmentStatusID":"8","companyTruncated":"ONCOtherapeutics \/ Celgene Corporation"},{"orgOrder":0,"company":"Moffitt Cancer Center","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2011","type":"Inapplicable","leadProduct":"Pomalidomide","moa":"CRL4(CRBN) E3 ubiquitin ligase","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Moffitt Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Moffitt Cancer Center \/ Bristol Myers Squibb","highestDevelopmentStatusID":"7","companyTruncated":"Moffitt Cancer Center \/ Bristol Myers Squibb"},{"orgOrder":0,"company":"ONCOtherapeutics","sponsor":"Celgene Corporation","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2012","type":"Inapplicable","leadProduct":"Pomalidomide","moa":"CRL4(CRBN) E3 ubiquitin ligase","graph1":"Oncology","graph2":"Phase II","graph3":"ONCOtherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ONCOtherapeutics \/ Celgene Corporation","highestDevelopmentStatusID":"8","companyTruncated":"ONCOtherapeutics \/ Celgene Corporation"},{"orgOrder":0,"company":"Bristol Myers 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Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Genmab \/ Undisclosed"},{"orgOrder":0,"company":"Johnson & Johnson Innovative Medicine","sponsor":"European Myeloma Network","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Daratumumab","moa":"||Lymphocyte differentiation antigen CD38","graph1":"Oncology","graph2":"Approved FDF","graph3":"Johnson & Johnson Innovative Medicine","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Johnson & Johnson Innovative Medicine \/ European Myeloma Network","highestDevelopmentStatusID":"15","companyTruncated":"Johnson & Johnson Innovative Medicine \/ European Myeloma Network"},{"orgOrder":0,"company":"Johnson & Johnson Innovative 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Treon, MD, PhD"},{"orgOrder":0,"company":"Celgene Corporation","sponsor":"Ajai Chari","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2014","type":"Inapplicable","leadProduct":"Pomalidomide","moa":"CRL4(CRBN) E3 ubiquitin ligase","graph1":"Oncology","graph2":"Phase II","graph3":"Celgene Corporation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Celgene Corporation \/ Ajai Chari","highestDevelopmentStatusID":"8","companyTruncated":"Celgene Corporation \/ Ajai Chari"}]

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                          01

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Sarclisa (isatuximab) is the first anti-CD38 therapy in combination with pomalidomide and Dexamethasone treatment for adult patients with multiple myeloma.

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          January 13, 2025

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Sarclisa (isatuximab) is the first anti-CD38 therapy in combination with pomalidomide and Dexamethasone treatment for adult patients with elapsed or refractory multiple myeloma.

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Lead Product(s) : Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Pomavid, a high-quality version of pomalidomide. Pomavid® is a new generation medication for the treatment of multiple myeloma, a type of blood cancer.

                          Product Name : Pomavid

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          June 07, 2024

                          Lead Product(s) : Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          NanoAlvand

                          04

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Sarclisa (isatuximab) is a antibody that binds to a specific epitope on the CD38 receptor on multiple myeloma (MM) cells. It is being evaluated in phase 3 clinical trials in combination with carfilzomib, lenalidomide & dexamethasone (KRd) for the treatme...

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          December 11, 2023

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          05

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Latest results from Phase 3 IKEMA clinical trial for Sarclisa®(isatuximab-irfc) in combination with carfilzomib and dexamethasone demonstrated a median PFS of 35.7 months, compared to 19.2 months in patients treated with Kd alone.

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          May 15, 2022

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          06

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Sponsor : Blackstone Life Sciences

                          Deal Size : $330.0 million

                          Deal Type : Collaboration

                          Details : For the Sarclisa® subcutaneous formulation delivery, Sanofi has partnered with drug delivery technology innovator company to advance the development of a subcutaneous delivery for Sarclisa® with the goal of offering a unique patient-centric treatment e...

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          March 15, 2022

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Blackstone Life Sciences

                          Deal Size : $330.0 million

                          Deal Type : Collaboration

                          Sanofi Company Banner

                          07

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : SARCLISA® continues to be evaluated in multiple ongoing Phase 3 clinical trials in combination with current standard treatments across the MM treatment continuum. It is also under investigation for the treatment of other hematologic malignancies and sol...

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          October 13, 2021

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          08

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Sarclisa is a monoclonal antibody that binds to a specific epitope on the CD38 receptor on MM cells. It is designed to work through multiple mechanisms of action including programmed tumor cell death (apoptosis) and immunomodulatory activity.

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          April 19, 2021

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          09

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The decision follows the Phase III IKEMA trial, which featured 302 patients with relapsed multiple myeloma across 69 centers spanning 16 countries. The study found that Sarclisa added to Kd reduced the risk of disease progression or death by 45%, versus ...

                          Product Name : Sarclisa

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 31, 2021

                          Lead Product(s) : Isatuximab,Dexamethasone,Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          10

                          Details : U.S. Food and Drug Administration has approved Breckenridge’s Abbreviated New Drug Application for Pomalidomide Capsules (generic for Pomalyst®).

                          Product Name : Undisclosed

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          November 13, 2020

                          Lead Product(s) : Pomalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Natco Pharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Breckenridge Pharmaceutical