

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Roche's Polivy Combination Confirms New Standard for Untreated Aggressive Lymphoma
Details : Polivy (polatuzumab vedotin) in combination with rituximab, cyclophosphamide, doxorubicin and prednisone is indicated in people with untreated diffuse large B-cell lymphoma.
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
December 08, 2024
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Polatuzumab Vedotin,Rituximab,Dexamethasone,Cisplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Polatuzumab Vedotin is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Lymphoma, Large B-Cell, Diffuse.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
July 28, 2023
Lead Product(s) : Polatuzumab Vedotin,Rituximab,Dexamethasone,Cisplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Polivy® (polatuzumab vedotin-piiq) is a first-in-class anti-CD79b antibody-drug conjugate (ADC). It binds to cancer cells such as CD79b and destroys these B cells through the delivery of an anti-cancer agent, which is thought to minimize the effects on ...
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
April 19, 2023
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Polivy® (polatuzumab vedotin-piiq) is a first-in-class anti-CD79b antibody-drug conjugate (ADC). It binds to cancer cells such as CD79b and destroys these B cells through the delivery of an anti-cancer agent, which is thought to minimize the effects on ...
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
March 09, 2023
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Polivy® intravenous infusion 30 mg and 140 mg [generic name: polatuzumab vedotin (genetical recombination)] for an additional indication of treatment of patients with previously untreated diffuse large B-cell lymphoma (DLBCL).
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 24, 2022
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Polivy® (polatuzumab vedotin-piiq) in combination with Rituxan® (rituximab) plus cyclophosphamide, doxorubicin and prednisone (R-CHP) for the treatment of people with previously untreated diffuse large B-cell lymphoma (DLBCL).
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 16, 2022
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Polatuzumab Vedotin,Rituximab,Hyaluronidase,Gemcitabine,Cisplatin,Dexamethasone,Granulocyte Colony Stimulating Factor
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Genentech
Deal Size : Inapplicable
Deal Type : Inapplicable
Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma
Details : Polatuzumab Vedotin is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Lymphoma, Large B-Cell, Diffuse.
Product Name : Undisclosed
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 11, 2022
Lead Product(s) : Polatuzumab Vedotin,Rituximab,Hyaluronidase,Gemcitabine,Cisplatin,Dexamethasone,Granulocyte Colony Stimulating Factor
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Genentech
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Loncastuximab Tesirine,Polatuzumab Vedotin
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ZYNLONTA® (loncastuximab tesirine-lpyl), is a CD19-directed antibody drug conjugate (ADC). Once bound to a CD19-expressing cell, ZYNLONTA is internalized by the cell, where enzymes release a pyrrolobenzodiazepine (PBD) payload.
Product Name : Zynlonta
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
June 29, 2022
Lead Product(s) : Loncastuximab Tesirine,Polatuzumab Vedotin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Approval is based on pivotal data from the phase III POLARIX study, where Polivy (Polatuzumab Vedotin) plus R-CHP significantly improved progression-free survival with comparable safety versus the standard of care, R-CHOP.
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
May 25, 2022
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Polivy plus R-CHP showed first clinically meaningful improvement in PFS with comparable safety in people with previously untreated diffuse large B-cell lymphoma (DLBCL) over the standard of care in more than 20 years.
Product Name : Polivy
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
March 25, 2022
Lead Product(s) : Polatuzumab Vedotin,Cyclophosphamide,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
