[{"orgOrder":0,"company":"Plexxikon","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"PLX51107","moa":"Bromodomain and extraterminal domain protein (BET)","graph1":"Oncology","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Plexxikon \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Undisclosed"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2013","type":"Inapplicable","leadProduct":"PLX7486","moa":"Granulocyte colony-stimulating factor receptor (G-CSF-R)","graph1":"Oncology","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Undisclosed"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Cogent Biosciences","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Bezuclastinib","moa":"c-KIT receptor||KIT*","graph1":"Oncology","graph2":"Phase III","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"10","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"PLX5622","moa":"Macrophage colony stimulating factor receptor","graph1":"Undisclosed","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Undisclosed"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"PLX5622","moa":"Macrophage colony stimulating factor receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Undisclosed"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"8","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"8","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"8","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2013","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"8","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"7","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Miscellaneous","year":"2013","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Plexxikon \/ Plexxikon","highestDevelopmentStatusID":"7","companyTruncated":"Plexxikon \/ Plexxikon"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Undisclosed"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2016","type":"Inapplicable","leadProduct":"PLX73086","moa":"Macrophage colony-stimulating factor 1 (CSF1)","graph1":"Oncology","graph2":"Phase I","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Plexxikon \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Plexxikon \/ Undisclosed"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Novellus","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Licensing Agreement","leadProduct":"Plixorafenib","moa":"Serine\/threonine-protein kinase B-raf","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Plexxikon \/ Novellus","highestDevelopmentStatusID":"7","companyTruncated":"Plexxikon \/ Novellus"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Hannah Choe","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"PLX51107","moa":"Bromodomain and extraterminal domain protein (BET)","graph1":"Immunology","graph2":"Phase I\/ Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Plexxikon \/ Hannah Choe","highestDevelopmentStatusID":"7","companyTruncated":"Plexxikon \/ Hannah Choe"},{"orgOrder":0,"company":"Plexxikon","sponsor":"Hope Rugo","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Pexidartinib","moa":"Macrophage colony stimulating factor receptor | Tyrosine-protein kinase receptor FLT3 | Stem cell growth factor receptor||Tyrosine-protein kinase receptor FLT3 | Macrophage colony stimulating factor receptor | Stem cell growth factor receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Plexxikon","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Plexxikon \/ Hope Rugo","highestDevelopmentStatusID":"7","companyTruncated":"Plexxikon \/ Hope Rugo"}]

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                          01

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX51107 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Graft vs Host Disease.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 02, 2021

                          Lead Product(s) : PLX51107

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Hannah Choe

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : Under the terms of the agreement, Plexxikon grants Novellus rights to research, develop, manufacture and exclusively commercialize PLX8394 worldwide.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 03, 2020

                          Lead Product(s) : Plixorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Novellus

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX51107 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 17, 2016

                          Lead Product(s) : PLX51107

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX73086 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          February 04, 2016

                          Lead Product(s) : PLX73086

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : CGT9486 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Gastrointestinal Stromal Tumors.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 30, 2015

                          Lead Product(s) : Bezuclastinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Cogent Biosciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX3397 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Melanoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 08, 2013

                          Lead Product(s) : Pexidartinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Daiichi Sankyo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX7486 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          March 05, 2013

                          Lead Product(s) : PLX7486

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX3397 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Glioblastoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 13, 2013

                          Lead Product(s) : Pexidartinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Daiichi Sankyo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX3397 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Breast Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 11, 2012

                          Lead Product(s) : Pexidartinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Hope Rugo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Global ChemShow
                          Not Confirmed
                          Global ChemShow
                          Not Confirmed

                          Details : PLX3397 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 03, 2012

                          Lead Product(s) : Pexidartinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Daiichi Sankyo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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