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    [{"orgOrder":0,"company":"UCB Pharma S.A","sponsor":"Advanz Pharma","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"BELGIUM","productType":"Other Small Molecule","year":"2020","type":"Acquisition","leadProduct":"Alprostadil","moa":"||EP1 receptor","graph1":"Psychiatry\/Psychology","graph2":"Approved FDF","graph3":"UCB Pharma S.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"UCB Pharma S.A \/ Advanz Pharma","highestDevelopmentStatusID":"15","companyTruncated":"UCB Pharma S.A \/ Advanz Pharma"},{"orgOrder":0,"company":"UCB Pharma S.A","sponsor":"Advanz Pharma","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"BELGIUM","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Alprostadil","moa":"||EP1 receptor","graph1":"Psychiatry\/Psychology","graph2":"Approved FDF","graph3":"UCB Pharma S.A","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"UCB Pharma S.A \/ Advanz Pharma","highestDevelopmentStatusID":"15","companyTruncated":"UCB Pharma S.A \/ Advanz Pharma"},{"orgOrder":0,"company":"Biopeutics","sponsor":"Medical Center of Vienna","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Alprostadil","moa":"||EP1 receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Biopeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Biopeutics \/ Medical Center of Vienna","highestDevelopmentStatusID":"10","companyTruncated":"Biopeutics \/ Medical Center of Vienna"},{"orgOrder":0,"company":"CSPC ZhongQi","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Alprostadil","moa":"||Prostanoid EP1 receptor | Prostanoid EP2 receptor","graph1":"Nephrology","graph2":"Phase II","graph3":"CSPC ZhongQi","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"CSPC ZhongQi \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CSPC ZhongQi \/ Inapplicable"}]

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                            01

                            Biopeutics

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                            Biopeutics

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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Medical Center of Vienna

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            End-Stage Heart Failure Sends News that Biopeutics Enters Phase 3 Clinical Trials

                            Details : Eubeatline (alprostadil), is a Prostaglandin E1 agonist, which is being evaluated for the treatment of severe heart failure in adults.

                            Product Name : Eubeatline

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 18, 2023

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Medical Center of Vienna

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            CSPC ZhongQi

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                            EPSC
                            Not Confirmed

                            CSPC ZhongQi

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                            EPSC
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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Explore the Efficacy of Alprostadil Liposomes Injection in the Prevention of CI-AKI

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 27, 2022

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            UCB Pharma S.A

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                            EPSC
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                            UCB Pharma S.A

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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved FDF

                            Sponsor : Advanz Pharma

                            Deal Size : $98.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Advanz Pharma Announces Definitive Agreement to Acquire The Rights To A Portfolio Of Alprostadil Products

                            Details : The alprostadil product portfolio consists of two established, niche, injectable Prostaglandin E1 formulations for the treatment of erectile disfunction and peripheral arterial occlusive disease.

                            Product Name : Prostavasin

                            Product Type : Other Small Molecule

                            Upfront Cash : $84.0 million

                            June 03, 2020

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved FDF

                            Sponsor : Advanz Pharma

                            Deal Size : $98.0 million

                            Deal Type : Agreement

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                            04

                            UCB Pharma S.A

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                            EPSC
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                            UCB Pharma S.A

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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved FDF

                            Sponsor : Advanz Pharma

                            Deal Size : $96.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Advanz Pharma Corp. Limited Closes Acquisition of the Rights to a Portfolio of Alprostadil Products from UCB S...

                            Details : Advanz get the rights to a portfolio of alprostadil products including, Prostavasin, Viridal, Vasaprostan and Edex, which consists of injectable Prostaglandin E1 formulations for the treatment of erectile disfunction and peripheral arterial occlusive dis...

                            Product Name : Prostavasin

                            Product Type : Other Small Molecule

                            Upfront Cash : $96.0 million

                            January 04, 2020

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved FDF

                            Sponsor : Advanz Pharma

                            Deal Size : $96.0 million

                            Deal Type : Acquisition

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                            05

                            CSPC ZhongQi

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                            EPSC
                            Not Confirmed

                            CSPC ZhongQi

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                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The Safety and Tolerability of Alprostadil Liposome for Injection in Healthy Adult Volunteers

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 13, 2018

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Rob Gruters

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                            EPSC
                            Not Confirmed

                            Rob Gruters

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                            EPSC
                            Not Confirmed
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                            Lead Product(s) : iHIVARNA-01,Alprostadil,Papaverine Hydrochloride,Phentolamine Mesylate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Institut d'Investigacions Biomèdiques | IrsiCaixa | Institute of Tropical Medicine, Belgium | Vrije Universiteit Brussel | Synapse bv | Asphalion | eTheRNA immunotherapies | CR2O | Hospital Clinic of Barcelona | Germans Trias i Pujol Hospital | Universita

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            iHIVARNA Clinical Trial in HIV Infected Individuals

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            September 05, 2016

                            Lead Product(s) : iHIVARNA-01,Alprostadil,Papaverine Hydrochloride,Phentolamine Mesylate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Institut d'Investigacions Biomèdiques | IrsiCaixa | Institute of Tropical Medicine, Belgium | Vrije Universiteit Brussel | Synapse bv | Asphalion | eTheRNA immunotherapies | CR2O | Hospital Clinic of Barcelona | Germans Trias i Pujol Hospital | Universita

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Seelos Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Seelos Therapeutics

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                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Seco...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 29, 2014

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Warner Chilcott Company, LLC

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Warner Chilcott Company, LLC

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : WC3036-12F,Alprostadil

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy & Safety of Single Dose Alprostadil Cream (2 Concentrations Enhancer) to Vehicle in Men w/Erectile Dy...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 13, 2013

                            Lead Product(s) : WC3036-12F,Alprostadil

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Christoph Hehrlein

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                            EPSC
                            Not Confirmed

                            Christoph Hehrlein

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                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Bosentan Hydrate,Alprostadil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Undisclosed

                            Sponsor : Johnson & Johnson

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prognostic Influence of Light Rheography Measurement of Patients With Secondary Raynaud Syndrome With Ulcers o...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 22, 2011

                            Lead Product(s) : Bosentan Hydrate,Alprostadil

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Undisclosed

                            Sponsor : Johnson & Johnson

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            UCB Pharma S.A

                            Belgium arrow
                            EPSC
                            Not Confirmed

                            UCB Pharma S.A

                            Belgium arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prostaglandin E1 in Outpatients With Intermittent Claudication

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 21, 2010

                            Lead Product(s) : Alprostadil,Inapplicable

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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