Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Parabilis Reports Positive Proof-of-Mechanism for ERG Degrader Program
Details : Potent and specific degradation of ERG has been achieved with Helicon™ peptide degraders both in vitro and in vivo, leading to substantial tumor growth inhibition in multiple mouse models.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Inapplicable
April 25, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $145.0 million
Deal Type : Series E Financing
FogPharma Secures $145 Mn Financing for Development of FOG-001 and Peptide Portfolio
Details : The financing will fund the ongoing clinical development of FOG-001, the company’s first-in-class intracellular TCF-blocking β-catenin inhibitor for locally advanced or metastatic solid tumors.
Product Name : FOG-001
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 03, 2024
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : RA Capital Management
Deal Size : $145.0 million
Deal Type : Series E Financing
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : FOG-001 first-in-class TCF-blocking β-catenin inhibitor proprietary and conformationally stabilized α-helical polypeptide (Helicon™) therapeutics, which being investigated for first-in-class TCF-blocking β-catenin inhibitor Advanced Solid Tumors.
Product Name : FOG-001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 06, 2023
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Arch Ventures
Deal Size : $178.0 million
Deal Type : Series D Financing
Details : Proceeds from the Series D financing will be used to advance and accelerate FogPharma’s growing pipeline of hyperstabilized α-helical (Helicon™) polypeptide therapeutics. FOG-001, a first-and-only-in-class direct TCF-blocking β-catenin inhibitor.
Product Name : FOG-001
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 21, 2022
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Arch Ventures
Deal Size : $178.0 million
Deal Type : Series D Financing
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
FogPharma Announces Selection of Clinical Development Candidate Directly Targeting β-Catenin
Details : FOG-001, a first-in-class direct TCF-blocking β-catenin inhibitor, pioneering Helicon modality, a new class of precision medicines that aim to combine the targeting strength and specificity of antibodies with the cell penetration of small molecules.
Product Name : FOG-001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 03, 2022
Lead Product(s) : FOG-001
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Venbio Partners
Deal Size : $107.0 million
Deal Type : Series C Financing
Details : FogPhama’s proprietary Helicon™ peptides represent a new class of precision medicines that combines the targeting strength and specificity of antibodies with the cell penetration of small molecules.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 03, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Venbio Partners
Deal Size : $107.0 million
Deal Type : Series C Financing