[{"orgOrder":0,"company":"Parabilis Medicines","sponsor":"Venbio Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Series C Financing","leadProduct":"Undisclosed","moa":"Beta-catenin","graph1":"Oncology","graph2":"Preclinical","graph3":"Parabilis Medicines","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Parabilis Medicines \/ Venbio Partners","highestDevelopmentStatusID":"4","companyTruncated":"Parabilis Medicines \/ Venbio Partners"},{"orgOrder":0,"company":"Parabilis Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"FOG-001","moa":"Beta-catenin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Parabilis Medicines","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Parabilis Medicines \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Parabilis Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Parabilis Medicines","sponsor":"Arch Ventures","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Series D Financing","leadProduct":"FOG-001","moa":"Beta-catenin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Parabilis Medicines","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Parabilis Medicines \/ Arch Ventures","highestDevelopmentStatusID":"7","companyTruncated":"Parabilis Medicines \/ Arch Ventures"},{"orgOrder":0,"company":"Parabilis Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"FOG-001","moa":"Beta-catenin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Parabilis Medicines","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Parabilis Medicines \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Parabilis Medicines \/ Inapplicable"},{"orgOrder":0,"company":"Parabilis Medicines","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Series E Financing","leadProduct":"FOG-001","moa":"Beta-catenin","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Parabilis Medicines","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Parabilis Medicines \/ RA Capital Management","highestDevelopmentStatusID":"7","companyTruncated":"Parabilis Medicines \/ RA Capital Management"},{"orgOrder":0,"company":"Parabilis Medicines","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2025","type":"Inapplicable","leadProduct":"Undisclosed","moa":"ERG","graph1":"Oncology","graph2":"Preclinical","graph3":"Parabilis Medicines","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Parabilis Medicines \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Parabilis Medicines \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Parabilis Medicines

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : Potent and specific degradation of ERG has been achieved with Helicon™ peptide degraders both in vitro and in vivo, leading to substantial tumor growth inhibition in multiple mouse models.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          April 25, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : The financing will fund the ongoing clinical development of FOG-001, the company’s first-in-class intracellular TCF-blocking β-catenin inhibitor for locally advanced or metastatic solid tumors.

                          Product Name : FOG-001

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 03, 2024

                          Lead Product(s) : FOG-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : RA Capital Management

                          Deal Size : $145.0 million

                          Deal Type : Series E Financing

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                          03

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : FOG-001 first-in-class TCF-blocking β-catenin inhibitor proprietary and conformationally stabilized α-helical polypeptide (Helicon™) therapeutics, which being investigated for first-in-class TCF-blocking β-catenin inhibitor Advanced Solid Tumors.

                          Product Name : FOG-001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 06, 2023

                          Lead Product(s) : FOG-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : Proceeds from the Series D financing will be used to advance and accelerate FogPharma’s growing pipeline of hyperstabilized α-helical (Helicon™) polypeptide therapeutics. FOG-001, a first-and-only-in-class direct TCF-blocking β-catenin inhibitor.

                          Product Name : FOG-001

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 21, 2022

                          Lead Product(s) : FOG-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Arch Ventures

                          Deal Size : $178.0 million

                          Deal Type : Series D Financing

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                          05

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : FOG-001, a first-in-class direct TCF-blocking β-catenin inhibitor, pioneering Helicon modality, a new class of precision medicines that aim to combine the targeting strength and specificity of antibodies with the cell penetration of small molecules.

                          Product Name : FOG-001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 03, 2022

                          Lead Product(s) : FOG-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : FogPhama’s proprietary Helicon™ peptides represent a new class of precision medicines that combines the targeting strength and specificity of antibodies with the cell penetration of small molecules.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 03, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Venbio Partners

                          Deal Size : $107.0 million

                          Deal Type : Series C Financing

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