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Treatment","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase III","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"July 2024","year":"2024","type":"Licensing Agreement","leadProduct":"Opevesostat","moa":"","url1":"","url2":"","graph1":"Oncology","graph2":"Phase III","graph3":"Orion Corporation","amount2":1.9199999999999999,"therapeuticAreaNew":"Oncology","highestDevelopmentStatusNew":"Phase III","highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","productSubType":"Small molecule","amount2New":1.9199999999999999,"dosageForm":"","sponsorNew":"Orion Corporation \/ Merck & Co","highestDevelopmentStatusID":"10","companyTruncated":"Orion Corp.."}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Through the license agreement, Merck will gain global rights to develop and commercialize MK-5684 (opevesostat), which is being evaluated for metastatic castration-resistant prostate cancer.

                          Product Name : MK-5684

                          Product Type : Small molecule

                          Upfront Cash : $290.0 million

                          July 01, 2024

                          Lead Product(s) : Opevesostat,Dexamethasone,Fludrocortisone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Partner/Sponsor/Collaborator : Merck & Co

                          Deal Size : $1,920.0 million

                          Deal Type : Licensing Agreement

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                          02

                          Details : Under the license agreement, Tenax will be developing and commercializing the TNX-103 (levosimendan) for the treatment of pulmonary hypertension with heart failure with preserved ejection fraction.

                          Product Name : TNX-103

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 20, 2024

                          Lead Product(s) : Levosimendan

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Recipient : Tenax Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Details : The net proceeds will be used to advance Lego's ADC pipeline including, LCB14, an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2).

                          Product Name : LCB14

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 16, 2024

                          Lead Product(s) : LCB14

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Recipient : LegoChem Biosciences

                          Deal Size : $410.9 million

                          Deal Type : Financing

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                          04

                          Details : Under the agreement, Orion gains access to Glykos’ proprietary ADC technologies, initiating an ADC program and will be responsible for the target selection, research, development, and commercialization ...

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 08, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Recipient : Glykos

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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