Drugs in Dev.
Ophthalmology
Phase I
China 
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Lead Product(s) : ZKY001
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase I Clinical Study of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defect
Details : ZKY001 is a drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Corneal Diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
August 20, 2025
Lead Product(s) : ZKY001
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lifitegrast
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lifitegrast Eye Drops in Healthy Subjects:Phase I Study
Details : Lifitegrast is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Dry Eye Syndromes.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 27, 2025
Lead Product(s) : Lifitegrast
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JMKX003948
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of JMKX003948 Ophthalmic Suspension in Healthy Participants
Details : JMKX003948 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Wet Macular Degeneration.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 18, 2025
Lead Product(s) : JMKX003948
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 8-Bromo-pet-cyclic gmps
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : National Institute of Allergy and Infectious Diseases
Deal Size : Undisclosed
Deal Type : Agreement
Drug Farm and NIH Partner to Develop Treatment for ROSAH Syndrome
Details : Under the terms of the agreement, Drug Farm will partner with NIAID to develop DF-003, a precision-targeted drug for the treatment of ROSAH syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 19, 2024
Lead Product(s) : 8-Bromo-pet-cyclic gmps
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : National Institute of Allergy and Infectious Diseases
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : HG202
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HG202 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Wet Macular Degeneration.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
October 02, 2024
Lead Product(s) : HG202
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 8-Bromo-pet-cyclic gmps
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug Farm Gets IND Clearance for Phase 1b of DF-003 in ROSAH Syndrome Patients
Details : DF-003 is a first-in-class, oral, potent, highly selective alpha-kinase 1 (ALPK1) inhibitor, which is curently being evaluated for the treatment of ROSAH syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 17, 2024
Lead Product(s) : 8-Bromo-pet-cyclic gmps
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Aceclidine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : LENZ Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Aceclidine is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Presbyopia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 21, 2024
Lead Product(s) : Aceclidine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : LENZ Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 8-Bromo-pet-cyclic gmps
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug Farm Receives Rare Pediatric Disease Designation for Df-003 To Treat Rosah Syndrome
Details : DF-003, a potent small molecule inhibitor of ALPK1, is in Phase 1 development for the treatment of ROSAH Syndrome, targeting immunity and inflammation.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 13, 2024
Lead Product(s) : 8-Bromo-pet-cyclic gmps
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : HG202
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Tianjin Medical University Eye Hospital | Gene Therapy Research Center, Shariati Hospital, Tehran University of Medical Sciences, Iran
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HG202 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Macular Degeneration.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 11, 2023
Lead Product(s) : HG202
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Tianjin Medical University Eye Hospital | Gene Therapy Research Center, Shariati Hospital, Tehran University of Medical Sciences, Iran
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IBI333
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IBI333 is a recombinant anti-VEGF-A and anti-VEGF-C bispecific fusion protein which can simultaneously bind and neutralize the activities of VEGF-A and VEGF-C angiogenesis inhibition and vascular leakage reduction.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 28, 2023
Lead Product(s) : IBI333
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
