Drugs in Dev.
Oncology
Preclinical
Sweden 
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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Orion Corporation
Deal Size : $3.6 million
Deal Type : Collaboration
Orion and Alligator Bioscience Amend their Agreement Concerning Two Bispecific Antibodies
Details : Orion will continue to developtwo bispecific antibodies, which are currently in late-stage pre-clinical development, successfully developed using Alligator’s RUBY bispecific format.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 19, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Orion Corporation
Deal Size : $3.6 million
Deal Type : Collaboration

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Lead Product(s) : 177-Lu SN201
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Spago Nanomedical Reports Favorable Data in Breast Cancer Model with Tumorad
Details : Tumorad (177Lu]Lu-SN201) is a ionisisng radiation emmiter, which is being evaluated for the treatment of 4T1 orthotopic triple-negative breast cancer.
Product Name : Tumorad
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 24, 2024
Lead Product(s) : 177-Lu SN201
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AT-108
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : $32.7 million
Deal Type : Series A Financing
Swedish Biotech Raises €30M for Gene Therapy in Solid Tumors
Details : The financing aims to support the ongoing development of the lead program AT-108. Currently, it is being evaluated in the preclinical trial studies for neoplasms in the form of tailored treatment.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
March 14, 2024
Lead Product(s) : AT-108
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : $32.7 million
Deal Type : Series A Financing

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Lead Product(s) : YAP–TEAD
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : National Center for Advancing Translational Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, NCATS will gain access to proprietary novel proteolysis-targeting degraders of TEAD, including YAP–TEAD, from Beactica to evaluate their efficacy in disease-relevant preclinical models for treatment of cancer.
Product Name : YAP–TEAD
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 26, 2023
Lead Product(s) : YAP–TEAD
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : National Center for Advancing Translational Sciences
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Day One Biopharmaceuticals
Deal Size : $316.0 million
Deal Type : Licensing Agreement
Day One Announces VRK1 License Agreement and Research Collaboration with Sprint Bioscience
Details : Under the agreement, Day One receives an exclusive license to develop and commercialize small molecule drug candidates targeting Vaccinia-related kinase 1 (VRK1), for pediatric and adult cancers with high unmet need.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $3.0 million
August 16, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Day One Biopharmaceuticals
Deal Size : $316.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Impilo is advancing its Tumor-Penetrating Nanocomplex platform, to provide a targeted delivery approach for a wide range of nucleic acid treatment modalities including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs) for solid tumor. ca...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
August 15, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : XNK04,Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Agreement
XNK Therapeutics Enters into Research Agreement with Global Pharma Company
Details : Under the research agreement, company's autologous natural killer (NK) cell therapy candidate XNK04 will be evaluated in combination with an ADCC competent PD-L1 inhibitor in liver cancer.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
May 04, 2023
Lead Product(s) : XNK04,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : BEA-17
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Oscotec
Deal Size : $178.0 million
Deal Type : Termination
Beactica Therapeutics and Oscotec Mutually Agree to Conclude Oncology Collaboration
Details : Under the agreement, Beactica Therapeutics will retain full exclusive global rights for further development and commercialization of the LSD1 programme, including BEA-17, a first-in-class small molecule targeted degrader of the epigenetic enzyme LSD1 and...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
April 04, 2023
Lead Product(s) : BEA-17
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Oscotec
Deal Size : $178.0 million
Deal Type : Termination

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Lead Product(s) : BEA-17
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BEA-17 is a first-in-class small molecule targeted degrader (non-PROTAC) of the epigenetic enzyme LSD1 and its co-factor CoREST. The compound has shown promising preclinical in vivo potentiation of immune-modulating treatments in several cancer forms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 01, 2023
Lead Product(s) : BEA-17
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : European Investment Bank
Deal Size : Undisclosed
Deal Type : Financing
Details : Anocca is using its advanced technologies to engineer next generationTCR-modified T-cell Therapy for the treatment of solid tumours with unmatched precision, speed, and scale.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 21, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : European Investment Bank
Deal Size : Undisclosed
Deal Type : Financing
