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Munich","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Isotope Technologies Munich \/ TerThera","highestDevelopmentStatusID":"4","companyTruncated":"Isotope Technologies Munich \/ TerThera"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Mitomycin

                          Therapeutic Area : Oncology

                          Study Phase : Preclinical

                          Sponsor : UroGen Pharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Details : Under the agreement, UroGen will develop a next-generation novel mitomycin-based formulation, UGN-103, UroGen’s RTGel® technology combined with medac’s licensed mitomycin, for urothelial cancers.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          January 17, 2024

                          Lead Product(s) : Mitomycin

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : UroGen Pharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Company Banner

                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The agreement will support the clinical development of Cellectar’s actinium-labeled PLE radiopharmaceuticals, including its Phase 1-ready compound, CLR 121225, for the treatment of solid tumors.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compound

                          Upfront Cash : Undisclosed

                          September 11, 2025

                          Lead Product(s) : 225-Ac CLR 121225

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Cellectar

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The two organizations aim to accelerate the development of radioligand therapies – highly specific, targeted therapies offering high efficacy with minimal side effects for cancer patients.

                          Product Name : Undislcosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 03, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : SCK CEN

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The partnership aims to advance Swarm's T-cell therapies for solid cancers. Cellex will supply cellular starting material and oversee process transfer, GMP manufacturing, and quality control.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          February 24, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Swarm Oncology

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Under the terms of the agreement, ITM will supply the therapeutic medical radioisotope, Ac-225 to advance the clinical development of SSO110 (225Ac-satoreotide tetraxetan) for treatment of neoplasms.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compound

                          Upfront Cash : Undisclosed

                          January 13, 2025

                          Lead Product(s) : 225-Ac Satoreotide Tetraxetan

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Ariceum Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Under the agreement, NorthStar will provide Ariceum with an Ac-225 radiolabelled compound. Ariceum will further develop SS0110 (Ac-225-satoreotide trizoxetan) for the treatment of SCLC.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Undisclosed

                          December 11, 2024

                          Lead Product(s) : 225-Ac Satoreotide Trizoxetan

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : NorthStar Medical Radioisotopes

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The agreement aims to develop an advanced preclinical stage first-in-class peptide 212Pb-based alpha radioligand therapies, for the treatment of solid tumors.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 13, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : ARTBIO

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The agreement will accelerate nuclear medicine initiatives by integrating ITM’s expertise in radioisotope production and development with TUM’s cutting-edge research capabilities in nuclear physics.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 24, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Technical University of Munich

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Through the acquisition, Pentixapharm will leverage the Glycotype portfolio of preclinical antibodies against multiple oncology including GT-001, which is being evaluated for breast and lung cancer.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          July 03, 2024

                          Lead Product(s) : GT-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : PentixaPharm

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : MDG2021, a TCR-T therapy targeting KRASG12D with HLA-A*11 being developed in combination with the Company’s PD1-41BB costimulatory switch protein, for solid tumors.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          June 20, 2024

                          Lead Product(s) : MDG2021,PD1-41BB

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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