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Compound","year":"2021","type":"Inapplicable","leadProduct":"177-Lu DOTA-TLX591","moa":"PSMA","graph1":"Oncology","graph2":"Phase II","graph3":"Telix Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Telix Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Telix Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Telix Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Radiolabeled Compound","year":"2021","type":"Inapplicable","leadProduct":"177-Lu DOTA-TLX591","moa":"PSMA","graph1":"Oncology","graph2":"Phase II","graph3":"Telix Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Telix Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Telix Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Radiopharm Theranostics","sponsor":"Medpace, Inc","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Radiolabeled Compound","year":"2025","type":"Inapplicable","leadProduct":"18-F FPIA","moa":"Pyruvate kinase","graph1":"Oncology","graph2":"Phase II","graph3":"Radiopharm Theranostics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Radiopharm Theranostics \/ Medpace, Inc","highestDevelopmentStatusID":"8","companyTruncated":"Radiopharm Theranostics \/ Medpace, Inc"},{"orgOrder":0,"company":"Clarity Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Radiolabeled Compound","year":"2020","type":"Inapplicable","leadProduct":"64-Cu SARTATE","moa":"SSTR2","graph1":"Oncology","graph2":"Phase II","graph3":"Clarity Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Clarity Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Clarity Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Clarity Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Radiolabeled Compound","year":"2020","type":"Inapplicable","leadProduct":"64-Cu SARTATE","moa":"SSTR2","graph1":"Oncology","graph2":"Phase II","graph3":"Clarity Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Clarity Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Clarity Pharmaceuticals \/ 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Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kazia Therapeutics \/ Lakshmi Nayak, MD","highestDevelopmentStatusID":"8","companyTruncated":"Kazia Therapeutics \/ Lakshmi Nayak, MD"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : The collaboration aims for the initiation of an investigator-initiated Phase II trial evaluating neoadjuvant eftilagimod alfa administered subcutaneously in HR+/HER2-negative breast cancer.

                          Product Name : Efti

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          September 22, 2025

                          Lead Product(s) : Eftilagimod Alpha

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : George Washington University Cancer Center

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : The proceeds will support the development of Kazia's GDC-0084 (paxalisib), a brain-penetrant dual PI3K/mTOR inhibitor currently in clinical trials for both brain cancer and advanced breast cancer.

                          Product Name : GDC-0084

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          August 01, 2025

                          Lead Product(s) : Paxalisib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $2.0 million

                          Deal Type : Private Placement

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                          03

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : Efti (eftilagimod alpha) in combination with pembrolizumab is being evaluated for the treatment of first line therapy in recurrent/metastatic head and neck squamous cell carcinoma (1L HNSCC).

                          Product Name : Efti

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          May 05, 2025

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : PTX-100 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Lymphoma, T-Cell, Cutaneous.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 03, 2025

                          Lead Product(s) : PTX-100

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : IMP321 (Eftilagimod Alpha) is an MHC class II agonist protein, being investigated in combination with pembrolizumab for the treatment of resectable soft tissue sarcoma (STS).

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          06

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : 18-F FPIA is a Radiolabeled Compounds drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Neoplasm Metastasis.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compound

                          Upfront Cash : Inapplicable

                          January 15, 2025

                          Lead Product(s) : 18-F FPIA

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Medpace, Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : SNT-5505 is a lysyl oxidase inhibitor small molecule drug candidate, which is currently being evaluated in combination with ruxolitinib for the treatment of myelofibrosis.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 10, 2024

                          Lead Product(s) : SNT-5505,Ruxolitinib Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : IMP321 (eftilagimod alpha), a soluble LAG-3 protein. It is being evaluated in combination with keytruda for first-line treatment of metastatic non-small cell lung cancer.

                          Product Name : Efti

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Merck & Co

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          09

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : AMP945 (narmafotinib) is a novel focal adhesion kinase (FAK) inhibitor. It is being evaluated in precliical studies for the treatment of patients with pancreatic cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          September 19, 2024

                          Lead Product(s) : AMP945,Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : IMP321 (Eftilagimod Alpha) is an APC activator protein, being investigated in combination with pembrolizumab being investigated for soft tissue sarcoma.

                          Product Name : Efti

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 18, 2024

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Merck & Co

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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