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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
GDC-0084 (paxalisib) is an oral PI3K/mTOR dual inhibitor, which is being evaluated for the treatment of patients with PI3K pathway mutation brain metastases.
IMP321 (eftilagimod alpha), a soluble LAG-3 protein and MHC Class II agonist that stimulates both innate and adaptive immunity. It is being evaluated in phase 2 clinial trials for first line treatment of metastatic non-small cell lung cancer & head & neck squamous cell cancer.
IMP321 (Eftilagimod Alpha) is an antigen presenting cell activator for the treatment of cancer. It is being investigated in combination with MSD’s anti-PD-1 therapy pembrolizumab as first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma.
IMP321 (eftilagimod alpha) is an antigen presenting cell activator for the treatment of cancer, capitalising on LAG-3’s to stimulate both innate and adaptive immunity. It is being investigated in phase II trial in combination with KEYTRUDA for NSCLC.
IMP321 (Eftilagimod Alpha) is an antigen presenting cell activator for the treatment of cancer, capitalising on LAG-3’s to stimulate both innate and adaptive immunity. It is being investigated in phase II trial in combination with KEYTRUDA for soft tissue sarcoma.
MDX-1097 (kappamab) targets a receptor called Kappa Myeloma Antigen (KMA) found only on the surface of myeloma cells in in combination with lenalidomide and dexamethasone in kappa-type multiple myeloma patients who had relapsed or become refractory to other treatment options.
IMP321 (Eftilagimod Alpha) is an antigen presenting cell activator for the treatment of cancer, capitalising on LAG-3’s to stimulate both innate and adaptive immunity. It is being investigated in phase II trial in soft tissue sarcoma in neoadjuvant setting.
IMP321 (eftilagimod alpha) binds and activates LAG-3 leading in expansion and proliferation of CD8+ (cytotoxic) T cells, CD4+ (helper) T cells, dendritic cells, NK cells, and monocytes. It is being investigated for NSCLC in combination with pembrolizumab.
IMP321 (eftilagimod alpha) soluble LAG-3 protein and MHC Class II agonist that stimulates both innate and adaptive immunity for the treatment of cancer. It is being investigated for non-small cell lung cancer.
IMP321 (Eftilagimod Alpha) is an antigen presenting cell activator for the treatment of cancer, capitalising on LAG-3’s to stimulate both innate and adaptive immunity. It is being investigated in phase II trial in soft tissue sarcoma in neoadjuvant setting.