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KINGDOM","productType":"Cell & Gene Therapy","year":"2025","type":"Acquisition","leadProduct":"CTM-N2D","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"TC BioPharm","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"TC BioPharm \/ CytoMed Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"TC BioPharm \/ CytoMed Therapeutics"},{"orgOrder":0,"company":"GSK","sponsor":"Nader Sanai","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"Risvutatug Rezetecan","moa":"CD276 | Top I","graph1":"Oncology","graph2":"Phase I","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"GSK \/ Nader Sanai","highestDevelopmentStatusID":"6","companyTruncated":"GSK \/ Nader Sanai"}]

    Find Oncology Drugs in Phase I Clinical Development in UNITED KINGDOM

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                            01

                            Quotient Sciences

                            United Kingdom
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                            Virtual BoothQuotient Sciences- Molecule to Cure. Fast.

                            Lead Product(s) : OXL001

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Oxilio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Oxilio Announces Start of Its First Clinical Trial With OXL001

                            Details : OXL001, has been developed utilising a novel bio-enabling platform technology, it has been taken into clinical studies which gives its immense potential as a pan-cancer therapy.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 06, 2022

                            Lead Product(s) : OXL001

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Oxilio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            Quotient

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                            02

                            GSK

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                            GSK

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                            Lead Product(s) : Risvutatug Rezetecan

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Nader Sanai

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (AD...

                            Details : GSK5764227 (Risvutatug Rezetecan) is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Glioblastoma.

                            Product Name : GSK5764227

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            December 05, 2025

                            Lead Product(s) : Risvutatug Rezetecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Nader Sanai

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            TC BioPharm

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                            TC BioPharm

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                            Lead Product(s) : CTM-N2D

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : CytoMed Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Cytomed Therapeutics Acquires UK T Cell Tech for Cancer Treatment in China, India

                            Details : Under the acquisition of CTM-N2D, a cell & gene therapy product, the deal aims to advance undisclosed key focus areas.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            November 18, 2025

                            Lead Product(s) : CTM-N2D

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : CytoMed Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            04

                            Theolytics

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                            Theolytics

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                            Lead Product(s) : THEO-260

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients

                            Details : THEO-260 is a Microorganism drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Ovarian Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            October 08, 2025

                            Lead Product(s) : THEO-260

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Healx

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                            Healx

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                            Lead Product(s) : Domatinostat,Sirolimus

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Healx

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Healx Enhances Cancer Recurrence Prevention with AI Platform and Vuja De Sciences Deal

                            Details : Under the agreement, Healx will aims to advance HLX-4310, an Investigational compounds being studied for the treatment of Osteosarcoma.

                            Product Name : HLX-4310

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 23, 2025

                            Lead Product(s) : Domatinostat,Sirolimus

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Healx

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            AstraZeneca

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                            AstraZeneca

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                            Lead Product(s) : Rilvegostomig

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : PAREXEL International Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants Wit...

                            Details : Rilvegostomig is a Antibody, Unconjugated drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            September 08, 2025

                            Lead Product(s) : Rilvegostomig

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : PAREXEL International Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Immunocore

                            United Kingdom arrow
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                            Immunocore

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                            Lead Product(s) : IMC-P115C

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of IMC-P115C in Advanced PRAME-Positive Cancers

                            Details : IMC-P115C is a Large Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 04, 2025

                            Lead Product(s) : IMC-P115C

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Hemogenyx Pharmaceuticals

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                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : HG-CT-1

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $0.7 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Hemogenyx raises £570,000 and Director's Dealing

                            Details : The net proceeds will be used for Phase I clinical trial of the Company's Chimeric Antigen Receptor T-cell therapy, HG-CT-1, aimed at treating relapsed/refractory acute myeloid leukemia.

                            Product Name : HG-CT-1

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Undisclosed

                            August 26, 2025

                            Lead Product(s) : HG-CT-1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $0.7 million

                            Deal Type : Financing

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                            09

                            Pheon Therapeutics

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                            Pheon Therapeutics

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                            Lead Product(s) : PHN-012

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of PHN-012 in Patients with Advanced Solid Tumors

                            Details : PHN-012 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Colonic Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            August 17, 2025

                            Lead Product(s) : PHN-012

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            AstraZeneca

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                            AstraZeneca

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                            Lead Product(s) : GC012F

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CAR T Therapy GC012F Targeting CD19/BCMA In Early-Line Myeloma

                            Details : GC012F is a Cell and Gene Therapy drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Multiple Myeloma.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            July 18, 2025

                            Lead Product(s) : GC012F

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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