
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : OLX75016
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Eli Lilly
Deal Size : Undisclosed
Deal Type : Licensing Agreement
OliX, Lilly Ink Global Deal for MASH & Cardiometabolic Indications
Details : Under the licensing agreement,Lilly will focus on the development and commercialization of OliX’s OLX75016, a Phase 1 candidate primarily targeting metabolic-associated steatohepatitis indications.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
February 10, 2025
Lead Product(s) : OLX75016
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Eli Lilly
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : OLX75016
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
OliX Pharmaceuticals Begins Patient Dosing in Phase 1 Trial of OLX75016 for MASH
Details : OLX75016 It is being developed as a novel treatment approach for metabolic dysfunctions associated with non-alcoholic fatty liver disease linked to obesity.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
February 13, 2024
Lead Product(s) : OLX75016
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OLX75016
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The company has received approval from the Alfred Human Research Ethics Committee to conduct a Phase 1 clinical trial of drug candidate OLX75016 for the treatment of non-alcohol steatohepatitis.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 22, 2023
Lead Product(s) : OLX75016
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OLX10212
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OLX10212 is a VEGF Modulator oligonucleotide drug administered via intravitreal injection, currently being investigated for the treatment of Age-Related Macular Degeneration.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
November 29, 2023
Lead Product(s) : OLX10212
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OLX72021
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OLX72021 an investigational RNAi therapeutic and acts to suppress the hormone activity that causes androgenic alopecia by reducing the expression of the androgen receptor (AR).
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
June 13, 2023
Lead Product(s) : OLX72021
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : DynamiCure
Deal Size : Undisclosed
Deal Type : Agreement
Details : Companies signed a memorandum of understanding, for developing an RNA-based antibody-drug conjugate (ADC) therapeutics at the Korea-US Digital·BioHealth Business Forum.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
May 10, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : DynamiCure
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : OLX10010
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OLX10010 is an asymmetric siRNA duplex with a cell-penetrating moiety attached to the 3’ of sense strand (cell-penetrating asymmetric siRNA, i.e. cp-asiRNA), targeting human connective tissue growth factor, which is a key factor in the development of h...
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
April 28, 2023
Lead Product(s) : OLX10010
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OLX10212
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OLX10212, an investigational RNAi therapeutic intended for the treatment of AMD. It targets inflammation pathways (blockade of VEGF) and offers increased specificity over conventional siRNA having the additional benefit of impermanence over gene therapy.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 27, 2023
Lead Product(s) : OLX10212
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OLX72021
Therapeutic Area : Dermatology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OLX72021 acts to suppress the hormone activity that causes androgenic alopecia by reducing the expression of the androgen receptor (AR)
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 23, 2023
Lead Product(s) : OLX72021
Therapeutic Area : Dermatology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OLX10212
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Trial Runners, LLC
Deal Size : Inapplicable
Deal Type : Inapplicable
Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration
Details : OLX10212 is a Oligonucleotide drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Wet Macular Degeneration.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 08, 2022
Lead Product(s) : OLX10212
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Trial Runners, LLC
Deal Size : Inapplicable
Deal Type : Inapplicable
