Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Positive Results of CONTESSA Presented at the 2020 San Antonio Breast Cancer Symposium (SABCS)
Details : CONTESSA is a multinational, multicenter, randomized, Phase 3 study of tesetaxel, an investigational, orally administered taxane, in patients with MBC. CONTESSA met the primary endpoint of improved PFS as assessed by the IRC.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
November 12, 2020
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Jefferies
Deal Size : $80.0 million
Deal Type : Public Offering
Odonate Therapeutics Announces Public Offering of Shares of Common Stock
Details : Odonate intends to use the proceeds from the proposed underwritten public offering of its shares of common stock for development, regulatory and commercial preparation activities relating to tesetaxel, as well as for working capital and general corporate...
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
August 27, 2020
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Jefferies
Deal Size : $80.0 million
Deal Type : Public Offering
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Odonate Therapeutics Announces Positive Top-line Results from CONTESSA
Details : CONTESSA met the primary endpoint of improved PFS as assessed by the IRC. Median PFS was 9.8 months for tesetaxel plus a reduced dose of capecitabine versus 6.9 months for the approved dose of capecitabine alone, an improvement of 2.9 months.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
August 24, 2020
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cohorts 2 and 3 of CONTESSA TRIO will expand on results from TOB203, a Phase 2 study that evaluated tesetaxel monotherapy in 38 patients with hormone receptor-positive, HER2-negative MBC.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
July 12, 2020
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CONTESSA is comparing tesetaxel dosed orally at 27 mg/m2 got each each 21-day cycle plus a reduced dose of capecitabine to the approved dose of capecitabine alone in patients with HER2 (-), HR (+) MBC previously treated with a taxane in the neoadjuvant o...
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
May 10, 2020
Lead Product(s) : Tesetaxel,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable