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Details:
Tesomet (tesofensine), is a novel, proprietary molecule, and investigational fixed-dose combination therapy of, a triple monoamine reuptake inhibitor and metoprolol (a beta-1 selective blocker).
Lead Product(s):
Tesofensine ,Metoprolol Tartrate
Therapeutic Area: Nutrition and Weight Loss
Product Name: Tesomet
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
May 23, 2022
Details:
Adults receiving Tesomet demonstrated statistically significant reductions in body weight and improvements in waist circumference and glycemic control.
Lead Product(s):
Tesofensine ,Metoprolol Tartrate
Therapeutic Area: Nutrition and Weight Loss
Product Name: Tesomet
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
July 26, 2021
Details:
The poster to be presented will highlight the results from a phase 2 clinical trial of Tesomet for hypothalamic obesity, at the 22nd European Congress of Endocrinology virtual annual meeting being held 5-9 September 2020.
Lead Product(s):
Tesofensine ,Metoprolol Tartrate
Therapeutic Area: Nutrition and Weight Loss
Product Name: Tesomet
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
August 24, 2020
Details:
The 26-week blinded phase 2 monotherapy trial with AM833 investigated safety, tolerability and efficacy for weight management in 706 people with obesity or overweight with at least one weight-related comorbidity.
Lead Product(s):
Fleroxacin
Therapeutic Area: Nutrition and Weight Loss
Product Name: AM833
Highest Development Status: Phase II
Product Type: Undisclosed
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
June 18, 2020
Details:
Study results showed that Tesomet was safe and well tolerated. Robust efficacy data reported statistically significant improvements in body weight, waist circumference, and glycemic control.
Lead Product(s):
Tesofensine
Therapeutic Area: Nutrition and Weight Loss
Product Name: Undisclosed
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
April 22, 2020
Details:
A total of 18 patients, of the original 21 who started the trial, have now continued into the open-label extension part of the study.
Lead Product(s):
Tesofensine
Therapeutic Area: Nutrition and Weight Loss
Product Name: Undisclosed
Highest Development Status: Phase II
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
March 18, 2020