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Details : The AT-1501 Phase 2a trial in ALS is an open label, dose escalating, safety and biomarker study. AT-1501 blocks activation of the CD40L pathway, that has been seen to improve muscle function, slow disease progression, and improve survival in a pre-clinic...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 02, 2020
Lead Product(s) : Tegoprubart
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Anelixis Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Novus Therapeutics Announces Acquisition of Anelixis Therapeutics
Details : Acquisition includes lead clinical-stage compound AT-1501, a next generation anti-CD40L antibody, in development for organ and cellular transplantation, autoimmune diseases, and neurodegenerative diseases.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
September 14, 2020
Lead Product(s) : Tegoprubart
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Anelixis Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : DPPC,Cholesteryl Palmitate
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Although the study did not achieve statistical significance for the primary efficacy endpoints, But the statistical trend were encouraging that favored the OP0201 treatment group with regard to resolution of middle ear effusion.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 01, 2020
Lead Product(s) : DPPC,Cholesteryl Palmitate
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : DPPC,Cholesteryl Palmitate
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Study is assessing the safety, tolerability, and efficacy of 20 mg/day intranasal OP0201 as an adjunct therapy to oral antibiotic treatment of acute otitis media in infants and 6 to 24 months olds.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 02, 2020
Lead Product(s) : DPPC,Cholesteryl Palmitate
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable