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SA","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"FRANCE","productType":"HPAPI","year":"2025","type":"Inapplicable","leadProduct":"Bimatoprost","moa":"FP receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Nicox SA","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Nicox SA \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Nicox SA \/ Inapplicable"},{"orgOrder":0,"company":"Nicox SA","sponsor":"Kowa Company","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"FRANCE","productType":"HPAPI","year":"2025","type":"Licensing Agreement","leadProduct":"Bimatoprost","moa":"FP receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Nicox SA","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0.029999999999999999,"dosageForm":"Ophthalmic Solution","sponsorNew":"Nicox SA \/ Kowa Company","highestDevelopmentStatusID":"10","companyTruncated":"Nicox SA \/ Kowa Company"}]

Find Clinical Drug Pipeline Developments & Deals by Nicox SA

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Under the licensing agreement, Kowa holds the Japanese rights to research & development and commercialize NCX 470 (bimatoprost). It is being evaluated for the treatment of ocular hypertension.

                          Product Name : NCX 470

                          Product Type : HPAPI

                          Upfront Cash : $3.2 million

                          May 27, 2025

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Kowa Company

                          Deal Size : $32.8 million

                          Deal Type : Licensing Agreement

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                          02

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : NCX 470 is a novel NO-donating bimatoprost eye drop which is currently under development for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension.

                          Product Name : NCX 470

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          May 14, 2025

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : NCX 470 is a novel NO-donating bimatoprost eye drop which is currently under development for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension.

                          Product Name : NCX 470

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          March 19, 2025

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : NCX 470 is a novel NO-donating bimatoprost eye drop which is currently under development for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension.

                          Product Name : NCX 470

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          March 03, 2025

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Zerviate (cetirizine ophthalmic solution) is exclusively licensed to Ocumension for development and commercialization in the Chinese and the majority of the Southeast Asian markets.

                          Product Name : Zerviate

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 04, 2024

                          Lead Product(s) : Cetirizine Dihydrochloride

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : OcuMension Therapeutics

                          Deal Size : $17.2 million

                          Deal Type : Licensing Agreement

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                          06

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : NCX 470 is a novel NO-donating bimatoprost eye drop which is currently under development for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension.

                          Product Name : NCX 470

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          December 02, 2024

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Soleus will acquire Nicox’s VYZULTA royalty, the first nitric oxide donating compound, indicated for the reduction of IOP in patients with open-angle glaucoma or ocular hypertension.

                          Product Name : Vyzulta

                          Product Type : HPAPI

                          Upfront Cash : Undisclosed

                          October 14, 2024

                          Lead Product(s) : Latanoprostene Bunod

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Soleus Capital

                          Deal Size : $16.5 million

                          Deal Type : Financing

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                          08

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Under the license agreement, Glaukos will fund and conduct NCX 1728 preclinical research activities evaluating it in glaucoma (including neuroprotection) and other retinal diseases.

                          Product Name : NCX 1728

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          September 23, 2024

                          Lead Product(s) : NCX 1728

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Glaukos

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          09

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : ZERVIATE (cetirizine hcl) is a histamine-1 (H1) receptor antagonist indicated for the treatment of ocular itching associated with allergic conjunctivitis.

                          Product Name : Zerviate

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 18, 2024

                          Lead Product(s) : Cetirizine Dihydrochloride

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Kowa will develop and commercialize NCX470 (bimatoprost) for lowering intraocular pressure in glaucoma patients under a recent agreement with Nicox.

                          Product Name : NCX 470

                          Product Type : HPAPI

                          Upfront Cash : $3.2 million

                          August 02, 2024

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Kowa Pharmaceuticals America

                          Deal Size : $32.8 million

                          Deal Type : Licensing Agreement

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