Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Bryostatin-1
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : BryoLogyx Inc
Deal Size : Undisclosed
Deal Type : Agreement
Details : BryoLogyx has entered into two agreements with Neurotrope for its preclinical data package and drug product for use of bryostatin-1 in an immuno-oncology application, and to supply Neurotrope with synthetic bryostatin-1 for use in clinical trials and com...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 06, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : BryoLogyx Inc
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : National Institutes of Health | National Institute on Aging
Deal Size : Inapplicable
Deal Type : Inapplicable
Bryostatin Treatment of Moderately Severe Alzheimer's Disease
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 03, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : National Institutes of Health | National Institute on Aging
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Worldwide Clinical Trials
Deal Size : Undisclosed
Deal Type : Agreement
Details : Neurotrope has entered into a services agreement with Worldwide Clinical Trials to support site recruitment and activation for the Company's ongoing Phase 2 study of bryostatin-1 in the treatment of moderately severe Alzheimer's disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 30, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Worldwide Clinical Trials
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The new Phase 2 clinical study, which is expected to enroll approximately 100 patients, will evaluate Bryostatin-1 in the absence of Namenda® (memantine) for a six-month period, which will include two 11-week dosing cycles.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 10, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : National Institutes of Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : National Institutes of Health
Deal Size : $2.7 million
Deal Type : Collaboration
Details : The Phase 2 clinical study will be conducted in collaboration with the National Institutes of Health. The study will evaluate the long-term therapeutic effect of Bryostatin-1 in the absence of Namenda® (memantine) in patients with AD.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 28, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : National Institutes of Health
Deal Size : $2.7 million
Deal Type : Collaboration
Lead Product(s) : Avanafil
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Recipient : Petros Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Details : Petros' cornerstone product would be Metuchen's Stendra® for erectile dysfunction. Petros' pipeline would include Metuchen's recently in-licensed product H-100 for Peyronie's disease, and it would include a business development program exploring variou...
Product Name : Stendra
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 18, 2020
Lead Product(s) : Avanafil
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Recipient : Petros Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Analysis to adjust for significant baseline imbalance in severe impairment battery scores between treatment groups shows improvement in cognitive function.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 22, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Worldwide Clinical Trials
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine
Details : Undisclosed
Product Name : Undisclosed
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
June 18, 2018
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Worldwide Clinical Trials
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 01, 2015
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Blanchette Rockefeller Neurosciences Insitute
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 21, 2014
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Blanchette Rockefeller Neurosciences Insitute
Deal Size : Inapplicable
Deal Type : Inapplicable