[{"orgOrder":0,"company":"Medlab Clinical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Controlled Substance","year":"2023","type":"Inapplicable","leadProduct":"Tetrahydrocannabinol","moa":"||Cannabinoid CB1 receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Medlab Clinical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Spray","sponsorNew":"Medlab Clinical \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Medlab Clinical \/ Undisclosed"},{"orgOrder":0,"company":"Mesoblast","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Cell & Gene Therapy","year":"2021","type":"Inapplicable","leadProduct":"Hyaluronic Acid","moa":"||estrogens","graph1":"Neurology","graph2":"Phase III","graph3":"Mesoblast","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Mesoblast \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Mesoblast \/ Undisclosed"},{"orgOrder":0,"company":"Mesoblast","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"Hyaluronic Acid","moa":"||estrogens","graph1":"Neurology","graph2":"Phase III","graph3":"Mesoblast","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Mesoblast \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Mesoblast \/ Undisclosed"},{"orgOrder":0,"company":"Mesoblast","sponsor":"Grunenthal","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Cell & Gene Therapy","year":"2021","type":"Inapplicable","leadProduct":"Hyaluronic Acid","moa":"||estrogens","graph1":"Neurology","graph2":"Phase III","graph3":"Mesoblast","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Mesoblast \/ Grunenthal","highestDevelopmentStatusID":"10","companyTruncated":"Mesoblast \/ Grunenthal"},{"orgOrder":0,"company":"Mesoblast","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Cell & Gene Therapy","year":"2024","type":"Inapplicable","leadProduct":"Hyaluronic Acid","moa":"||estrogens","graph1":"Neurology","graph2":"Phase III","graph3":"Mesoblast","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Mesoblast \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Mesoblast \/ Undisclosed"},{"orgOrder":0,"company":"Medical Developments International","sponsor":"PERUKI | Quintiles Inc","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Methoxyflurane","moa":"GABA-A receptor; anion channel | Glycine receptor (alpha-1\/beta)","graph1":"Neurology","graph2":"Phase III","graph3":"Medical Developments International","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Medical Developments International \/ PERUKI | Quintiles Inc","highestDevelopmentStatusID":"10","companyTruncated":"Medical Developments International \/ PERUKI | Quintiles Inc"},{"orgOrder":0,"company":"Medical Developments International","sponsor":"ORION Clinical Services","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Methoxyflurane","moa":"GABA-A receptor; anion channel | Glycine receptor (alpha-1\/beta)","graph1":"Neurology","graph2":"Phase III","graph3":"Medical Developments International","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Medical Developments International \/ ORION Clinical Services","highestDevelopmentStatusID":"10","companyTruncated":"Medical Developments International \/ ORION Clinical Services"},{"orgOrder":0,"company":"Invex Therapeutics","sponsor":"Premier Research Group | University Hospital Birmingham | University of Iowa","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Peptide, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Exenatide","moa":"Glucagon-like peptide 1 receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Invex Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Invex Therapeutics \/ Premier Research Group | University Hospital Birmingham | University of Iowa","highestDevelopmentStatusID":"10","companyTruncated":"Invex Therapeutics \/ Premier Research Group | University Hospital Birmingham | University of Iowa"},{"orgOrder":0,"company":"RDC Clinical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Palmitoylethanolamide","moa":"TNF-alpha receptor","graph1":"Neurology","graph2":"Phase III","graph3":"RDC Clinical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"RDC Clinical \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"RDC Clinical \/ Undisclosed"},{"orgOrder":0,"company":"Medlab Clinical","sponsor":"George Clinical | WriteSource Medical Pty Ltd","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"AUSTRALIA","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Delta 9 Tetrahydrocannabinol","moa":"Undisclosed","graph1":"Neurology","graph2":"Phase III","graph3":"Medlab Clinical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Medlab Clinical \/ George Clinical | WriteSource Medical Pty Ltd","highestDevelopmentStatusID":"10","companyTruncated":"Medlab Clinical \/ George Clinical | WriteSource Medical Pty Ltd"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Revascor (rexlemestrocel-L) is preparation of immunoselected and culture-expanded mesenchymal precursor cells. It is being evaluated for the treatment of moderate to severe chronic low back pain.

                          Product Name : Revascor

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          July 21, 2024

                          Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : NanaBis™ (tetrahydrocannabinol) is an investigative novel analgesic for cancer patients comprising equal parts of CBD and THC encapsulated in Medlab’s patented delivery platform, NanoCelle®. NanaBis™ is applied to the oro-buccal membrane for rapid...

                          Product Name : NanaBis

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          January 12, 2023

                          Lead Product(s) : Tetrahydrocannabinol,Cannabidiol

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Lead Product(s) : Exenatide

                          Therapeutic Area : Neurology

                          Study Phase : Phase III

                          Sponsor : Premier Research Group | University Hospital Birmingham | University of Iowa

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Presendin (Exenatide) is a Peptide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Pseudotumor Cerebri.

                          Product Name : Presendin

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          April 26, 2022

                          Lead Product(s) : Exenatide

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Premier Research Group | University Hospital Birmingham | University of Iowa

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Phase 3 trial of its allogeneic cell therapy MPC-06-ID ( rexlemestrocel-L), showed a durable reduction in back pain lasting at least three years from a single intra-discal injection in patients with chronic low back pain (CLBP) associated with degenerati...

                          Product Name : Revascor

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          January 11, 2022

                          Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : A key objective of MPC-06-ID (rexlemestrocel-L) is to demonstrate reduction in pain and opioid usage and and position rexlemestrocel-L as a potential opioid-sparing agent.

                          Product Name : Revascor

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          December 15, 2021

                          Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Grunenthal

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Palmitoylethanolamide is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Migraine Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 16, 2021

                          Lead Product(s) : Palmitoylethanolamide

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Lead Product(s) : Delta 9 Tetrahydrocannabinol

                          Therapeutic Area : Neurology

                          Study Phase : Phase III

                          Sponsor : George Clinical | WriteSource Medical Pty Ltd

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Delta 9 Tetrahydrocannabinol is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Cancer Pain.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          March 22, 2021

                          Lead Product(s) : Delta 9 Tetrahydrocannabinol

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : George Clinical | WriteSource Medical Pty Ltd

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : A single injection of rexlemestrocel-L may provide a durable, and effective opioid-sparing therapy for patients with chronic inflammatory back pain due to degenerative disc disease. Greatest benefits were seen when administered earlier in the disease pro...

                          Product Name : Revascor

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          February 10, 2021

                          Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Methoxyflurane is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Acute Pain.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 12, 2017

                          Lead Product(s) : Methoxyflurane

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : PERUKI | Quintiles Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Aquaexpo
                          Not Confirmed
                          Aquaexpo
                          Not Confirmed

                          Details : Methoxyflurane is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Pain.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 19, 2011

                          Lead Product(s) : Methoxyflurane

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : ORION Clinical Services

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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