Drugs in Dev.
Neurology
Phase II
Ireland 
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Lead Product(s) : Suvecaltamide
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
SynOx Therapeutics Announces $75m Series B Round to Fund Phase 3 Trial for TGCT Treatment
Details : JZP385 (suvecaltamide) is an investigational, highly selective and state-dependent modulator of T-type calcium channels, being evaluated in adult patients with moderate to severe essential tremor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 20, 2024
Lead Product(s) : Suvecaltamide
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

A Study of JZP541 in Adults With Irritability Associated With Autism Spectrum Disorder
Details : JZP541 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Autism Spectrum Disorder.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
February 17, 2023

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Lead Product(s) : Suvecaltamide
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Suvecaltamide in Adults With Moderate to Severe Residual Tremor in Parkinson's Disease
Details : Suvecaltamide is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Parkinson Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 08, 2022
Lead Product(s) : Suvecaltamide
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Prothena Presents New Data for Alzheimer's and Parkinson's Disease Programs at AD/PD 2022
Details : Results showed that participants with PD who were treated with prasinezumab for two years showed slower decline of Movement Disorder Society-Unified Parkinson’s Disease Rating Scale Part 3 scores relative to participants treated with prasinezumab for o...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 16, 2022

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Lead Product(s) : Suvecaltamide
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : JZP385 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Essential Tremor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 17, 2021
Lead Product(s) : Suvecaltamide
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Prasinezumab
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : $60.0 million
Deal Type : Collaboration
Prothena Announces Achievement of $60 Million Milestone From Roche
Details : Company has earned a $60 million milestone from its worldwide collaboration with Roche based on the first patient dosed in the Phase 2b PADOVA study of prasinezumab in patients with early Parkinson's disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
May 10, 2021
Lead Product(s) : Prasinezumab
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : $60.0 million
Deal Type : Collaboration

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Lead Product(s) : Cannabidiol
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GWP42003-P is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Autism Spectrum Disorder.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
February 09, 2021
Lead Product(s) : Cannabidiol
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Prasinezumab
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The study will be designed to further assess the efficacy of prasinezumab by expanding upon the patient population enrolled in PASADENA to include patients with early Parkinson’s disease on stable levodopa therapy.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 20, 2020
Lead Product(s) : Prasinezumab
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : F. Hoffmann-La Roche
Deal Size : Inapplicable
Deal Type : Inapplicable

Prothena Announces Updated Timing of Presentation for Phase 2 PASADENA Study Results
Details : Company will present Part 1 of the Phase 2 PASADENA study of prasinezumab in early Parkinson’s disease. Results from Part 1 of the Phase 2 PASADENA study of prasinezumab were selected as an oral Top Abstract presentation at the upcoming Virtual 2020 MD...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 03, 2020

Details : The study did not achieve the primary goal, but did show signs of efficacy. Roche has begun further clinical development preparation and is reviewing the results from PASADENA Study Part 1.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 22, 2020

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