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National Institute on Aging | Universidad de Antioquia","highestDevelopmentStatusID":"9","companyTruncated":"Banner Health \/ National Institute on Aging | Universidad de Antioquia"},{"orgOrder":0,"company":"WanBangDe Pharmaceutical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CHINA","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Fordine","moa":"Acetylcholinesterase","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"WanBangDe Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet, Controlled Release","sponsorNew":"WanBangDe Pharmaceutical \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"WanBangDe Pharmaceutical \/ Undisclosed"},{"orgOrder":0,"company":"Shanghai Zhimeng Biopharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CHINA","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"CB03-154","moa":"Androgen receptor","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"Shanghai Zhimeng Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Shanghai Zhimeng Biopharma \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Shanghai Zhimeng Biopharma \/ Undisclosed"},{"orgOrder":0,"company":"Biohaven Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"BHV-8000","moa":"Undisclosed","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"Biohaven Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biohaven Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Biohaven Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Praxis Precision Medicines","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"PRAX-628","moa":"NaV Channel","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"Praxis Precision Medicines","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Praxis Precision Medicines \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Praxis Precision Medicines \/ Undisclosed"}]

    Find Neurology Drugs in Phase II/III Clinical Development in UNITED STATES

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                            01

                            Shanghai Zhimeng Biopharma

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                            Shanghai Zhimeng Biopharma

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                            Lead Product(s) : CB03-154

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CB03-154 Dosing Safety and Efficacy In ALS Adults

                            Details : CB03-154 is a drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Amyotrophic Lateral Sclerosis.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            July 24, 2025

                            Lead Product(s) : CB03-154

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            WanBangDe Pharmaceutical

                            China arrow
                            ESCRS
                            Not Confirmed

                            WanBangDe Pharmaceutical

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                            ESCRS
                            Not Confirmed
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                            Lead Product(s) : Fordine

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Huperzine A CR Tablets Safety and Efficacy In Mild-Moderate Alzheimer’s Dementia

                            Details : Huperzine A is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Alzheimer Disease.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 15, 2025

                            Lead Product(s) : Fordine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Praxis Precision Medicines

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                            ESCRS
                            Not Confirmed

                            Praxis Precision Medicines

                            U.S.A arrow
                            ESCRS
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                            Lead Product(s) : PRAX-628

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PRAX-628 Double-blind Trial in Adults with Focal Seizures to Assess Efficacy & Safety

                            Details : PRAX-628 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Seizures.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 31, 2025

                            Lead Product(s) : PRAX-628

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Banner Health

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                            ESCRS
                            Not Confirmed

                            Banner Health

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                            ESCRS
                            Not Confirmed
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                            Lead Product(s) : Donanemab

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : National Institute on Aging | Universidad de Antioquia

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Donanemab ± RG6289 Safety & Efficacy In PSEN1 E280A Mutation Carriers with AD

                            Details : Donanemab is a Antibody drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Alzheimer Disease.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 30, 2025

                            Lead Product(s) : Donanemab

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : National Institute on Aging | Universidad de Antioquia

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            PharmaTher

                            Canada arrow
                            ESCRS
                            Not Confirmed

                            PharmaTher

                            Canada arrow
                            ESCRS
                            Not Confirmed
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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PharmaTher’s Ketamine Review Extended by FDA with New Goal Set for Aug 2025

                            Details : Ketarx (ketamine) is a NMDA receptor antagonist, being investigated for the management of pain, depression etc.

                            Product Name : Ketarx

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            May 16, 2025

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Biohaven Pharmaceuticals

                            U.S.A arrow
                            ESCRS
                            Not Confirmed

                            Biohaven Pharmaceuticals

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                            ESCRS
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                            Lead Product(s) : BHV-8000

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BHV-8000 Safety and Efficacy In Early Parkinson's Disease

                            Details : BHV-8000 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Parkinson Disease.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 16, 2025

                            Lead Product(s) : BHV-8000

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Universiti Putra Malaysia

                            Country arrow
                            ESCRS
                            Not Confirmed

                            Universiti Putra Malaysia

                            Country arrow
                            ESCRS
                            Not Confirmed
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                            Lead Product(s) : Bionerv

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : BREGO Life Sciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy And Tolerability Of Alpha Lipoic Acid And Vitamin B Preparation In Carpal Tunnel Syndrome

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 23, 2025

                            Lead Product(s) : Bionerv

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : BREGO Life Sciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Anavex Life Sciences

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                            ESCRS
                            Not Confirmed

                            Anavex Life Sciences

                            U.S.A arrow
                            ESCRS
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                            Lead Product(s) : Blarcamesine

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anavex Reports Positive Long-Term Data From Alzheimer’s Trial

                            Details : ANAVEX2-73 (blarcamesine) is an oral drug that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is under phase 2/3 clinical development for treating Alzheimer's disease.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 05, 2025

                            Lead Product(s) : Blarcamesine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Acumen Pharmaceuticals

                            U.S.A arrow
                            ESCRS
                            Not Confirmed

                            Acumen Pharmaceuticals

                            U.S.A arrow
                            ESCRS
                            Not Confirmed
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                            Lead Product(s) : Sabirnetug,Hyaluronidase Enzyme

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Acumen Reports Phase 1 Data for Subcutaneous Sabirnetug in Healthy Volunteers

                            Details : ACU193 (sabirnetug) is a humanized monoclonal antibody (mAb), it selectively targets toxic soluble AβOs which is the primary underlying cause of the neurodegenerative process in alzheimer’s disease.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 19, 2025

                            Lead Product(s) : Sabirnetug,Hyaluronidase Enzyme

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            PharmaTher

                            Canada arrow
                            ESCRS
                            Not Confirmed

                            PharmaTher

                            Canada arrow
                            ESCRS
                            Not Confirmed
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                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PharmaTher Receives US FDA Approval Goal Date for Ketamine

                            Details : Ketarx (ketamine) is a NMDA receptor antagonist, which is being evaluated as a potential treatment for mental health, and neurological disorders like parkinsons.

                            Product Name : Ketarx

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            March 11, 2025

                            Lead Product(s) : Ketamine Hydrochloride

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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