[{"orgOrder":0,"company":"Pharmaleads","sponsor":"IACTA Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"FRANCE","productType":"Other Small Molecule","year":"2021","type":"Collaboration","leadProduct":"IC 800","moa":"Undisclosed","graph1":"Neurology","graph2":"IND Enabling","graph3":"Pharmaleads","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Topical","sponsorNew":"Pharmaleads \/ IACTA Pharmaceuticals","highestDevelopmentStatusID":"5","companyTruncated":"Pharmaleads \/ IACTA Pharmaceuticals"},{"orgOrder":0,"company":"EG 427","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"FRANCE","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"EG110A","moa":"Botulinum toxin fragment","graph1":"Neurology","graph2":"IND Enabling","graph3":"EG 427","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"EG 427 \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"EG 427 \/ Inapplicable"},{"orgOrder":0,"company":"EG 427","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"FRANCE","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"EG110A","moa":"Botulinum toxin fragment","graph1":"Neurology","graph2":"IND Enabling","graph3":"EG 427","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"EG 427 \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"EG 427 \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : EG110A is a gene therapy for the treatment which works by silencing the type-C neurons, being developed for Neurogenic Detrusor Overactivity in Spinal Cord Injury patients.

                          Product Name : EG110A

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          June 24, 2024

                          Lead Product(s) : EG110A

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : EG110A is based on company's unique non-replicative HSV-1 vector platform. It is being evaluated in preclinical studies for neurogenic detrusor overactivity (NDO) and overactive bladder (OAB).

                          Product Name : EG110A

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 01, 2024

                          Lead Product(s) : EG110A

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Under the terms of these agreements, Pharmaleads and Pharmaleads Greater China have granted IACTA an exclusive, worldwide, royalty-bearing license to lead the clinical and commercial development of IC800 (acute) and IC805 and other DENKI drugs from Pharm...

                          Product Name : IC 800

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 01, 2021

                          Lead Product(s) : IC 800

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : IACTA Pharmaceuticals

                          Deal Size : $100.0 million

                          Deal Type : Collaboration

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                          04

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : AlgoTherapeutix has received approval from the ethics committee and the regulatory authority in the Czech Republic to initiate a Phase 1 clinical trial with ATX01.

                          Product Name : ATX01

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 15, 2020

                          Lead Product(s) : Amitriptyline Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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