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    [{"orgOrder":0,"company":"Calcilytix Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"GERMANY","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Encaleret","moa":"calcium receptor antagonists","graph1":"Nephrology","graph2":"Phase III","graph3":"Calcilytix Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Tablet, Film Coated","sponsorNew":"Calcilytix Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Calcilytix Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Calcilytix Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"GERMANY","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Encaleret","moa":"calcium receptor antagonists","graph1":"Nephrology","graph2":"Phase III","graph3":"Calcilytix Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Tablet, Film Coated","sponsorNew":"Calcilytix Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Calcilytix Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"GERMANY","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"BI690517","moa":"ALDOS","graph1":"Nephrology","graph2":"Phase III","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Boehringer Ingelheim GmbH \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Boehringer Ingelheim GmbH \/ Inapplicable"},{"orgOrder":0,"company":"Calcilytix Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"GERMANY","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Encaleret","moa":"calcium receptor","graph1":"Nephrology","graph2":"Phase III","graph3":"Calcilytix Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Calcilytix Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Calcilytix Therapeutics \/ Undisclosed"}]

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                            01

                            Boehringer Ingelheim GmbH

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                            SCI Medicinal Chemistry
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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Empagliflozin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EMPAgliflozin Safety and Efficacy In Children/Adolescents with CKD

                            Details : Empagliflozin is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Renal Insufficiency, Chronic.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 06, 2025

                            Lead Product(s) : Empagliflozin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Boehringer Ingelheim GmbH

                            Germany arrow
                            SCI Medicinal Chemistry
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                            Boehringer Ingelheim GmbH

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
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                            Lead Product(s) : BI690517

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EASi-KIDNEYâ„¢ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 01, 2024

                            Lead Product(s) : BI690517

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
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                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bayer to Start Phase III Study with Finerenone in Adults with Chronic Kidney Disease and Type 1 Diabetes

                            Details : Kerendia (finerenone) is a non-steroidal mineralocorticoid receptor antagonist and was approved by the FDA to reduce the risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization ...

                            Product Name : Kerendia

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 22, 2023

                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Bayer AG

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                            SCI Medicinal Chemistry
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                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
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                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bayer to Start Phase III Study with Finerenone in Adults with Chronic Kidney Disease and Type 1 Diabetes

                            Details : Kerendia/Firialta (finerenone) is a non-steroidal, selective mineralocorticoid receptor antagonist that has been shown to block harmful effects of MR overactivation. It has been granted marketing authorization for expanded indication in China for chronic...

                            Product Name : Kerendia

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 22, 2023

                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
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                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
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                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Dec...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 13, 2023

                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
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                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
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                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            New Kerendia™ (finerenone) Data Show Impact of Early Albuminuria Reduction in Patients with Chronic Kidney D...

                            Details : Kerendia (finerenone) is a non-steroidal, selective mineralocorticoid receptor (MR) antagonist that has been shown to block harmful effects of MR overactivation. It is being evaluated for the treatment of chronic kidney disease and type 2 diabetes.

                            Product Name : Kerendia

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 11, 2023

                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Boehringer Ingelheim GmbH

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed

                            Boehringer Ingelheim GmbH

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Empagliflozin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Eli Lilly

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Accepts Supplemental New Drug Application for Jardiance® For Adults with Chronic Kidney Disease

                            Details : Jardiance (empagliflozin) is an inhibitor of the sodium-glucose co-transporter 2 (SGLT2), which leads in lowering renal reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion.

                            Product Name : Jardiance

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 20, 2023

                            Lead Product(s) : Empagliflozin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Eli Lilly

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Calcilytix Therapeutics

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed

                            Calcilytix Therapeutics

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
                            • fda
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                            • WHO-GMP
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                            Lead Product(s) : Encaleret

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 11, 2023

                            Lead Product(s) : Encaleret

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed

                            Bayer AG

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE...

                            Details : Undisclosed

                            Product Name : Kerendia

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 13, 2022

                            Lead Product(s) : Finerenone

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Boehringer Ingelheim GmbH

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed

                            Boehringer Ingelheim GmbH

                            Germany arrow
                            SCI Medicinal Chemistry
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Empagliflozin

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Eli Lilly

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Landmark EMPA-KIDNEY Trial Showed Significant Benefit Of Jardiance® In Reducing Kidney Disease Progression Or...

                            Details : JARDIANCE (empagliflozin) is a prescription medicine used to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure, when the heart cannot pump enough blood to the rest of your body.

                            Product Name : Jardiance

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 11, 2022

                            Lead Product(s) : Empagliflozin

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Eli Lilly

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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