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              Novartis Pharmaceuticals Corporation

              • Development Update

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              SWITZERLAND Switzerland

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              BIO Digital 2021

              Participation Not Confirmed

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              Novartis Presents Promising Interim Phase II Data of Potential First-in-Class Oral Therapy Iptacopan in Rare Renal Disease C3 Glomerulopathy

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              Lead Product(s): Iptacopan

              Therapeutic Area: Nephrology Product Name: LNP023

              Highest Development Status: Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable October 26, 2020

              Details:

              Data presented at the ASN 2020 Annual Meeting shows that investigational iptacopan effectively and safely reduced proteinuria in patients with C3 glomerulopathy.

              Novartis Pharmaceuticals Corporation

              • Development Update

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              SWITZERLAND Switzerland

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              Novartis Received European Medicines Agency (EMA) PRIME Designation for Iptacopan (LNP) in C3 Glomerulopathy (C3G)

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              Lead Product(s): Iptacopan

              Therapeutic Area: Nephrology Product Name: LNP023

              Highest Development Status: Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable October 09, 2020

              Details:

              Iptacopan is a first-in-class oral, small-molecule, reversible inhibitor of factor B, a key serine protease of the alternative pathway of the complement cascade.

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