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    [{"orgOrder":0,"company":"Neoleukin Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"NL-CVX1","moa":"SARS-CoV-2 S","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Neoleukin Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Neoleukin Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Neoleukin Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Neoleukin Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Protein","year":"2022","type":"Inapplicable","leadProduct":"NEO-TRA1","moa":"IL-2 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Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"NL-201","moa":"IL-2 receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Neoleukin Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Neoleukin Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Neoleukin Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Neoleukin Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"NL-201","moa":"IL-2 receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Neoleukin Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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    Find Clinical Drug Pipeline Developments & Deals by Neoleukin Therapeutics

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                            01

                            Neoleukin Therapeutics

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                            Neoleukin Therapeutics

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                            Lead Product(s) : NGN-401

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase I/ Phase II

                            Sponsor : Neurogene

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Neurogene Announces Closing of Merger with Neoleukin Therapeutics and Concurrent Private Placement of $95 Mill...

                            Details : The combined company will focus on advancing Neurogene’s pipeline of differentiated genetic medicines, including NGN-401, a clinical-stage product for Rett syndrome, which uses novel gene regulation technology for a potential best-in-class profile.

                            Product Name : NGN-401

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            December 19, 2023

                            Lead Product(s) : NGN-401

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Neurogene

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            02

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Lead Product(s) : NGN-401

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase I/ Phase II

                            Sponsor : Neurogene

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Neurogene and Neoleukin Announce Definitive Merger Agreement

                            Details : The combined company will focus on advancing Neurogene’s pipeline of differentiated genetic medicines, including NGN-401, a clinical-stage product for Rett syndrome, which uses novel gene regulation technology for a potential best-in-class profile.

                            Product Name : NGN-401

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 18, 2023

                            Lead Product(s) : NGN-401

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Neurogene

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            03

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Lead Product(s) : NEO-TRA1

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Presents Preclinical Data on NEO-TRA1 at American Society of Hematology (ASH) Annual Me...

                            Details : NEO-TRA1, a precision-tuned agonist of the IL-2 receptor beta and gamma subunits that is targeted to and selectively expands inhibitory T-regulatory cells.

                            Product Name : NEO-TRA1

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            December 12, 2022

                            Lead Product(s) : NEO-TRA1

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Lead Product(s) : NL-201,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Announces Multiple Presentations at American Association for Cancer Research (AACR) Ann...

                            Details : NL-201 is world’s first computationally designed de novo protein therapeutic, positioned as a combined IL-2 and IL-15 agonist designed to improve tolerability and activity by eliminating the alpha receptor binding interface for the trreatment of cancer...

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            August 03, 2022

                            Lead Product(s) : NL-201,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Lead Product(s) : NL-201,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Announces First Patient Treated in Combination Arm of Phase 1 Trial Evaluating NL-201 i...

                            Details : NL-201 is a de novo agonist of the IL-2 and IL-15 receptors, designed to expand cancer-fighting CD8 T cells and natural killer (NK) cells without any bias toward cells expressing the alpha receptor subunit (CD25).

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            May 16, 2022

                            Lead Product(s) : NL-201,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Lead Product(s) : NL-201,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Announces Oral Presentation at 64th American Society of Hematology (ASH) Annual Meeting

                            Details : NL-201, is a combined IL-2 and IL-15 agonist designed to improve tolerability and activity by eliminating the alpha receptor binding interface.

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 11, 2022

                            Lead Product(s) : NL-201,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Pharmex
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                            Lead Product(s) : NL-201

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Receives Clinical Hold Letter from U.S. FDA Related to CMC Assay Development for NL-201

                            Details : The FDA has informed Neoleukin that it needs to develop a new assay that more precisely measures the amount of protein being administered and demonstrate with this assay that dose and administration procedures will accurately deliver the intended dose of...

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            August 01, 2021

                            Lead Product(s) : NL-201

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Neoleukin Therapeutics

                            U.S.A arrow
                            Pharmex
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                            Neoleukin Therapeutics

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                            Pharmex
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                            Lead Product(s) : NL-201

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Announces Abstract Accepted for Presentation at the SITC 2020

                            Details : Poster titled "NL-201, a de novo IL-2/IL-15 agonist, demonstrates enhanced in vivo antitumor activity in combination with multiple cancer immunotherapies" will be presented at the conference.

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 14, 2020

                            Lead Product(s) : NL-201

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Neoleukin Therapeutics

                            U.S.A arrow
                            Pharmex
                            Not Confirmed

                            Neoleukin Therapeutics

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                            Pharmex
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                            Lead Product(s) : NL-201,Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Presents Preclinical Combination Data for NL-201 at Society for Immunotherapy of Cancer...

                            Details : NL-201 enhances activity of checkpoint inhibitors and tumor-targeting antibodies and increases immune cell stimulation.

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 11, 2020

                            Lead Product(s) : NL-201,Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Neoleukin Therapeutics

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                            Pharmex
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                            Neoleukin Therapeutics

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                            Pharmex
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                            Lead Product(s) : NL-201

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neoleukin Therapeutics Provides Update on COVID-19 Impact on Corporate and Clinical Development Activities

                            Details : Neoleukin remains focused on its efforts to support an Investigational New Drug Application for its lead therapeutic, NL-201, and is working with key vendors to assess any potential impacts.

                            Product Name : NL-201

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            September 04, 2020

                            Lead Product(s) : NL-201

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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