Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Clinical Study of Neflamapimod in Patients with Primary Progressive Aphasia
Details : Neflamapimod is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Primary Progressive Nonfluent Aphasia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 24, 2025
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of Oral Neflamapimod Effect on Motor Recovery After Acute Ischaemic Stroke
Details : Neflamapimod is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Ischemic Stroke.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 23, 2025
Lead Product(s) : Neflamapimod
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CervoMed Reports Positive Phase 2b Neflamapimod Data in Lewy Body Dementia
Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 10, 2025
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : CervoMed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 10, 2025
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : CervoMed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CervoMed Announces Topline Data from RewinD-LB Phase 2b Trial in Dementia with Lewy Bodies
Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CervoMed Announces Orphan Drug Designation for Neflamapimod for Frontotemporal Dementia
Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of frontotemporal dementia.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 27, 2024
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CervoMed Completes Enrollment in Phase 2b Trial of Neflamapimod for Dementia
Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 06, 2024
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
CervoMed Completes Phase 2b RewinD-LB Trial of Neflamapimod in DLB
Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 15, 2024
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : RA Capital Management
Deal Size : $149.4 million
Deal Type : Private Placement
CervoMed Announces $149.4 Million Private Placement Financing with Investors
Details : The company intends to use net proceeds for research and development of VX-745 (neflamapimod), an orally administered small molecule inhibiting p38MAP kinase alpha.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : $50.0 million
March 28, 2024
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : RA Capital Management
Deal Size : $149.4 million
Deal Type : Private Placement
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : CervoMed
Deal Size : Undisclosed
Deal Type : Merger
CervoMed Announces Completion of Merger with EIP Pharma
Details : The Combined company will pursue late-stage clinical development of oral VX-745 (neflamapimod), a small molecule brain penetrant that inhibits p38MAP kinase alpha (p38a), for the treatment of dementia with Lewy bodies.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 16, 2023
Lead Product(s) : Neflamapimod
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : CervoMed
Deal Size : Undisclosed
Deal Type : Merger