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    [{"orgOrder":0,"company":"Neurocrine Biosciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"NBI-921352","moa":"Sodium channel protein type VIII alpha subunit","graph1":"Neurology","graph2":"Phase II","graph3":"Neurocrine Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Neurocrine Biosciences \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Neurocrine Biosciences \/ Undisclosed"},{"orgOrder":0,"company":"Neurocrine Biosciences","sponsor":"Xenon Pharmaceuticals Inc","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"NBI-921352","moa":"Sodium channel protein type VIII alpha subunit","graph1":"Neurology","graph2":"Phase 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Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Neurocrine Biosciences \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Neurocrine Biosciences \/ Undisclosed"},{"orgOrder":0,"company":"Xenon Pharmaceuticals Inc","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CANADA","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"NBI-921352","moa":"Sodium channel protein type VIII alpha subunit","graph1":"Undisclosed","graph2":"Phase I","graph3":"Xenon Pharmaceuticals Inc","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Xenon Pharmaceuticals Inc \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Xenon Pharmaceuticals Inc \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals for NBI-921352

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    NBI-921352

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                            01

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Xenon Pharmaceuticals Provides Update on Partnered Program with Neurocrine Biosciences

                            Details : NBI-921352, an investigational, selective sodium channel 1.6 inhibitor (Nav1.6) currently under development in adult patients with focal onset seizures (FOS), failed to demonstrate meaningful reduction in seizure frequency.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 09, 2023

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neurocrine Biosciences Presents Demographic and Clinical Characteristics Data of Pediatric Patients with SCN8A...

                            Details : NBI-921352 is an investigational, selective sodium channel 1.6 inhibitor (Nav1.6) currently under development for the potential treatment of SCN8A developmental and epileptic encephalopathy (SCN8A-DEE) in children and adults.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 02, 2022

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications ...

                            Details : NBI-921352 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Epilepsy, Generalized.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 09, 2022

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants Wit...

                            Details : NBI-921352 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Developmental and Epileptic Encephalopathy.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 07, 2022

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Xenon Pharmaceuticals Inc

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                            Xenon Pharmaceuticals Inc

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Xenon Pharmaceuticals Announces Collaboration with Neurocrine Biosciences Achieves $15.0 Million Regulatory Mi...

                            Details : Xenon has an ongoing collaboration with Neurocrine Biosciences to develop treatments for epilepsy. Neurocrine Biosciences has an exclusive license to XEN901, now known as NBI-921352, a selective Nav1.6 sodium channel inhibitor.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $50.0 million

                            January 12, 2022

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

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                            06

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Me...

                            Details : NBI-921352 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Epilepsy, Generalized.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 16, 2021

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Xenon Pharmaceuticals Inc

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Xenon Pharmaceuticals Announces Collaboration with Neurocrine Biosciences Achieves $10.0 Million Regulatory Mi...

                            Details : Xenon ongoing collaboration with Neurocrine Biosciences to develop treatments including XEN901, now known as NBI-921352 a clinical stage selective Nav1.6 sodium channel inhibitor with potential in SCN8A developmental and epileptic encephalopathy and othe...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $50.0 million

                            September 08, 2021

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

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                            08

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephal...

                            Details : NBI-921352 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Developmental and Epileptic Encephalopathy.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 05, 2021

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neurocrine Biosciences and Xenon Pharmaceuticals Provide Regulatory Update on Ongoing Collaboration to Develop...

                            Details : U.S. Food and Drug Administration (FDA) Requests Additional Non-Clinical Data to Support Dose Justification Before Initiation of a Phase II Clinical Trial with NBI-921352 in Pediatric SCN8A-DEE Patients.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 08, 2020

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Xenon Pharmaceuticals Inc

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of XEN901

                            Details : XEN901 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 15, 2018

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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