[{"orgOrder":0,"company":"National Institute on Aging","sponsor":"National Institute on Aging","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"CS6253","moa":"ABCA1","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Sulfiram","moa":"Aldehyde dehydrogenase","graph1":"Nutrition and Weight Loss","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ Undisclosed"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Acumen Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"ACU193","moa":"Amyloid beta A4 protein (APP)","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Alzheon","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Valiltramiprosate","moa":"Amyloid-beta A4 protein","graph1":"Neurology","graph2":"Phase III","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"10","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Alzheon","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Funding","leadProduct":"Valiltramiprosate","moa":"Amyloid-beta A4 protein","graph1":"Neurology","graph2":"Phase III","graph3":"National Institute on Aging","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0.050000000000000003,"dosageForm":"Tablet","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"10","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"National Institute on Aging","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"FINLAND","productType":"Vaccine","year":"2021","type":"Funding","leadProduct":"AV-1959R","moa":"Amyloid-beta-plaque||Amyloid-beta\/Tau","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"National Institute on Aging","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"FINLAND","productType":"Vaccine","year":"2022","type":"Funding","leadProduct":"AV-1959D","moa":"Amyloid-beta-protein","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"National Institute on Aging","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"FINLAND","productType":"Vaccine","year":"2022","type":"Funding","leadProduct":"DNA Vaccine","moa":"Amyloid-beta-protein","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Injection","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"National Institute on Aging","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"FINLAND","productType":"Vaccine","year":"2022","type":"Funding","leadProduct":"Beta-Amyloid Vaccine","moa":"Beta-amyloid","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Cassava Sciences","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Simufilam","moa":"Filamin-A","graph1":"Neurology","graph2":"Phase III","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"10","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Cassava Sciences","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Simufilam","moa":"Filamin-A","graph1":"Neurology","graph2":"Phase III","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet, Film Coated","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"10","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Athira Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"ATH-1017","moa":"HGF receptor","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"9","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Allyx Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"BMS-984923","moa":"Metabotropic glutamate receptor 5 (mGluR5)","graph1":"Undisclosed","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Capsule","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Jupiter Orphan Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Plant Extract\/Herbal","year":"2020","type":"Inapplicable","leadProduct":"Resveratrol","moa":"NLRP3\/SIRT1","graph1":"Undisclosed","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"ImmunoBrain Checkpoint","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"ISRAEL","productType":"Antibody, Unconjugated","year":"2021","type":"Funding","leadProduct":"IBC-Ab002","moa":"PDL1","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Infusion","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Aphios","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Funding","leadProduct":"Bryoid","moa":"PKC","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"NYU Langone Health","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Protein","moa":"Protein","graph1":"Nutrition and Weight Loss","graph2":"Undisclosed","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"1","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Neuronascent","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"NNI-362","moa":"S6K1","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Liquid, Suspension","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Neuronascent","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"NNI-362","moa":"S6K1","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Liquid, Suspension","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Adicet Bio","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Dactolisib","moa":"Serine\/threonine-protein kinase mTOR | PI3-kinase class I","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"8","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"resTORbio","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Funding","leadProduct":"Dactolisib","moa":"Serine\/threonine-protein kinase mTOR | PI3-kinase class I","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"10","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"NYU Langone Health","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Escitalopram Oxalate","moa":"Serotonin transporter","graph1":"Neurology","graph2":"Phase IV","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"11","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Cognition Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"CT1812","moa":"TMEM97","graph1":"Neurology","graph2":"Phase II","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"8","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Cognition Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Radiolabeled Compound","year":"2022","type":"Inapplicable","leadProduct":"14-C CT1812","moa":"Sigma-2 receptor","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Cognition Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"CT1812","moa":"Sigma intracellular receptor 2 (TMEM97)","graph1":"Neurology","graph2":"Phase II","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"8","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Cognition Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"CT1812","moa":"Sigma intracellular receptor 2 (TMEM97)","graph1":"Neurology","graph2":"Phase II","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"8","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Oligomerix","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Funding","leadProduct":"OLX-07010","moa":"Tau aggregation","graph1":"Neurology","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"AKAVA Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Funding","leadProduct":"AKV9","moa":"Undisclosed","graph1":"Neurology","graph2":"IND Enabling","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"5","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"University of California","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Funding","leadProduct":"CNDR-51997","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"National Institute on Aging","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"4","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"National Institute on Aging","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Xenon Gas","moa":"Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"6","companyTruncated":"National Institute on Aging \/ National Institute on Aging"},{"orgOrder":0,"company":"National Institute on Aging","sponsor":"Neurodon","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"IND Enabling","graph3":"National Institute on Aging","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"National Institute on Aging \/ National Institute on Aging","highestDevelopmentStatusID":"5","companyTruncated":"National Institute on Aging \/ National Institute on Aging"}]

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                          01

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : Xenon Gas is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 25, 2025

                          Lead Product(s) : Xenon Gas

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Recipient : General Biophysics LLC

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : The funding will support Akava’s lead compound, NU-9 (AKV9). It is being evaluated for the treatment of Alzheimer’s disease and frontotemporal dementia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          December 17, 2024

                          Lead Product(s) : AKV9

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Recipient : AKAVA Therapeutics

                          Deal Size : $7.3 million

                          Deal Type : Funding

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                          03

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : The funding will support the company in developing anti-CCR5 nanoparticles for treating patients suffering from Alzheimer’s disease.

                          Product Name : Bryoid

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 11, 2024

                          Lead Product(s) : Bryoid

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Recipient : Aphios

                          Deal Size : Undisclosed

                          Deal Type : Funding

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                          04

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : BMS-984923 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 09, 2024

                          Lead Product(s) : BMS-984923

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Recipient : Allyx Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : The proceeds will be used to prepare a potential disease-modifying Alzheimer’s treatment, CNDR-51997, which prevented tau from becoming detached from microtubules, for future clinical trials.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          August 21, 2024

                          Lead Product(s) : CNDR-51997

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Recipient : University of California

                          Deal Size : $6.9 million

                          Deal Type : Funding

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                          06

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : The funding will be used for continued development and Investigational New Drug (IND)-enabling studies to support clinical translation of the company's small molecule activators of the SERCA enzyme for Alzheimer's disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 03, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Recipient : Neurodon

                          Deal Size : $3.0 million

                          Deal Type : Funding

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                          07

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : CS6253 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Alzheimer Disease.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 28, 2023

                          Lead Product(s) : CS6253

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Recipient : Artery Therapeutics, Inc.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : This is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Frailty Pre-frail.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          July 27, 2023

                          Lead Product(s) : Protein

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Undisclosed

                          Recipient : NYU Langone Health

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : CT1812 binds selectively to the sigma-2 receptor complex which is involved in the regulation of key cellular processes, that are damaged by toxic interaction with soluble beta amyloid oligomers and currently in development for mild-to-moderate Alzheimerâ...

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 28, 2023

                          Lead Product(s) : CT1812

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Recipient : Cognition Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          The Battery Show
                          Not Confirmed
                          The Battery Show
                          Not Confirmed

                          Details : PTI-125 (Simufilam) is Cassava Sciences’ proprietary, small molecule (oral) drug that restores the normal shape and function of altered filamin A (FLNA) protein in the brain.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 18, 2022

                          Lead Product(s) : Simufilam

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Recipient : Cassava Sciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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