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Find Clinical Drug Pipeline Developments & Deals by NanoViricides
The drug NV-CoV-2 contains the Company's nanoviricide active agent, NV-387, which has shown strong broad-spectrum antiviral activity not only against multiple coronaviruses, but also against RSV and in a model for Smallpox therapeutics.
NV-CoV-2 (NV-387) was designed to mimic sulfated proteoglycans that a large number of virus families bind to as the first step in infecting a cell. It may possess significant antiviral activity against many other virus families in addition to MPox and Smallpox virus infections.
NV-CoV-2 (NV-387) was designed to mimic sulfated proteoglycans that a large number of virus families bind to as the first step in infecting a cell. It may possess significant antiviral activity against many other virus families in addition to coronaviruses.
NV-CoV-2 (NV-387) is a first-in-class chemical nanomachine that acts by a novel mechanism of action is re-Infection blocker. which is invetigated for the treatment of covid-19 infection.
NV-CoV-2 (NV-387) is a first-in-class chemical nanomachine that acts by a novel mechanism of action is re-Infection blocker. which is invetigated for the treatment of covid-19 infection.
NV-CoV-2 (NV-387) was designed to mimic sulfated proteoglycans that a large number of virus families bind to as the first step in infecting a cell. It may possess significant antiviral activity against many other virus families in addition to coronaviruses.
Under this Agreement, Karveer has the right to commercialize the Company's COVID drugs NV-CoV-2 and NV-CoV-2-R in India. To enable commercialization, Karveer has undertaken Clinical Development and Evaluation and is sponsoring these two drugs in India for this purpose.
The Company has also demonstrated the ability of NV-387 to encapsulate and improve the pharmacokinetics and pharmacodynamics of a very difficult drug, namely remdesivir, that is formulated in a cyclodextrin-based formulation at present (Veklury® Gilead).
In this well-known assay, NV-CoV-2 was as effective as the neutralizing antibody in reducing the virus infection. This study demonstrates that NV-CoV-2 attacks the SARS-CoV-2 pseudovirion particles and renders them incapable of binding to the ACE2 positive cells.
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