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    [{"orgOrder":0,"company":"Nanoscope Therapeutics","sponsor":"National Eye Institute","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Funding","leadProduct":"Sonpiretigene Isteparvovec","moa":"MCO","graph1":"Ophthalmology","graph2":"IND Enabling","graph3":"Nanoscope Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Nanoscope Therapeutics \/ National Eye Institute","highestDevelopmentStatusID":"5","companyTruncated":"Nanoscope Therapeutics \/ National Eye Institute"},{"orgOrder":0,"company":"Nanoscope Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"MCO-020","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"IND 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Inapplicable"},{"orgOrder":0,"company":"Nanoscope Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"vMCO-010","moa":"MCO","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Nanoscope Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Nanoscope Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Nanoscope Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Nanoscope Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"vMCO-010","moa":"MCO","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Nanoscope Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Nanoscope Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Nanoscope Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Nanoscope Therapeutics","sponsor":"Verana Health","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Collaboration","leadProduct":"Sonpiretigene Isteparvovec","moa":"MCO","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Nanoscope Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Nanoscope Therapeutics \/ Verana Health","highestDevelopmentStatusID":"8","companyTruncated":"Nanoscope Therapeutics \/ Verana 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Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Nanoscope Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Nanoscope Therapeutics \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Nanoscope Therapeutics

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                            01

                            Nanoscope Therapeutics

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                            Nanoscope Therapeutics

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                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Verana Health

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Verana & Nanoscope Collaborate on Retinitis Pigmentosa Research

                            Details : The collaboration aims fot the development and commercialization of MCO-010 (sonpiretigene isteparvovec), an optogenetic gene therapy designed to restore vision and potentially slow neurodegeneration.

                            Product Name : MCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            February 25, 2025

                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Verana Health

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Nanoscope Therapeutics

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                            Nanoscope Therapeutics

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                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Reports Positive Results from Trial Of MCO-010 for Retinitis Pigmentosa

                            Details : MCO-010 (sonpiretigene isteparvovec), an AAV-based vector carrying an multi-characteristic opsin (MCO) gene cassette, is being tested for retinitis pigmentosa.

                            Product Name : MCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            March 26, 2024

                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Nanoscope Therapeutics

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                            Nanoscope Therapeutics

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                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Therapeutics Announces Positive Topline Results from Phase 2b RESTORE Trial of MCO-010 for the Treat...

                            Details : MCO-010 (sonpiretigene isteparvovec) is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy for vision restoration in advanced retinitis pigmentosa (RP).

                            Product Name : MCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            March 30, 2023

                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Nanoscope Therapeutics

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                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : vMCO-010

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Therapeutics Announces Completion of Enrollment in STARLIGHT Phase 2 Clinical Trial of MCO-010 Optog...

                            Details : This multicenter, randomized, double-masked, sham-controlled, dose-ranging study will evaluate 2 dose levels of vMCO-010 in up to 18 subjects with retinitis pigmentosa (9 per dose).

                            Product Name : vMCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            September 13, 2022

                            Lead Product(s) : vMCO-010

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Nanoscope Therapeutics

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                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : vMCO-010

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Announces Presentations at the 22nd Euretina Congress

                            Details : The purpose of the study is to evaluate the safety and efficacy of a single intravitreal injection of virally-carried Multi-Characteristic Opsin (vMCO-010).

                            Product Name : vMCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 29, 2022

                            Lead Product(s) : vMCO-010

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Nanoscope Therapeutics

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                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : vMCO-010

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Therapeutics to Present at the Retina Forum 2022

                            Details : This multicenter, randomized, double-masked, sham-controlled, dose-ranging study will evaluate 2 dose levels of vMCO-010 in up to 18 subjects with retinitis pigmentosa (9 per dose). Nine subjects will receive sham injection.

                            Product Name : vMCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 26, 2022

                            Lead Product(s) : vMCO-010

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Nanoscope Therapeutics

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                            IMCAS Asia
                            Not Confirmed

                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : MCO-020

                            Therapeutic Area : Ophthalmology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Therapeutics to Present at the 3rd Annual Gene Therapy for Ophthalmic Disorders Meeting

                            Details : Nanoscope’s MCO-020 gene therapy program is based on targeted laser-delivery of optogenes to areas of geographic atrophy in advanced AMD patients, and currently undergoing IND-enabling studies.

                            Product Name : MCO-020

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 09, 2022

                            Lead Product(s) : MCO-020

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope's Vision Restoring Optogenetic Gene Therapy to be Featured in Multiple Presentations as part of ARVO...

                            Details : vMCO-010, an investigational AAV gene therapy designed to restore functional vision to patients with severe vision loss due to retinal degeneration, demonstrated a favorable safety profile and several patients experienced restoration of vision in Phase 1...

                            Product Name : MCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 26, 2022

                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Nanoscope Therapeutics

                            U.S.A arrow
                            IMCAS Asia
                            Not Confirmed

                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nanoscope Therapeutics co-Founder and President to Present at World Orphan Drug Congress Europe 2021, Nov. 17,...

                            Details : Nanoscope Therapeutics lead product MCO-010, is in a Phase 2b multicenter, randomized, double-masked, sham controlled clinical trial in the U.S. for treatment of retinitis pigmentosa.

                            Product Name : MCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            November 15, 2021

                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Nanoscope Therapeutics

                            U.S.A arrow
                            IMCAS Asia
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                            Nanoscope Therapeutics

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                            IMCAS Asia
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                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Ophthalmology

                            Study Phase : IND Enabling

                            Sponsor : National Eye Institute

                            Deal Size : $1.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Nanoscope Awarded $1.5M Phase 2B SBIR Grant to Advance Ambient Light Activatable Opsin Gene Therapy to Restore...

                            Details : Nanoscope’s lead MCO gene therapy, MCO-010, is in a late-stage Phase 2b trial for retinitis pigmentosa (RP) in the US. MCO-010 has orphan drug designations for RP and Stargardt disease from the US Food and Drug Administration.

                            Product Name : MCO-010

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 14, 2021

                            Lead Product(s) : Sonpiretigene Isteparvovec

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : IND Enabling

                            Sponsor : National Eye Institute

                            Deal Size : $1.5 million

                            Deal Type : Funding

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