
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Verana Health
Deal Size : Undisclosed
Deal Type : Collaboration
Verana & Nanoscope Collaborate on Retinitis Pigmentosa Research
Details : The collaboration aims fot the development and commercialization of MCO-010 (sonpiretigene isteparvovec), an optogenetic gene therapy designed to restore vision and potentially slow neurodegeneration.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
February 25, 2025
Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Verana Health
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Nanoscope Reports Positive Results from Trial Of MCO-010 for Retinitis Pigmentosa
Details : MCO-010 (sonpiretigene isteparvovec), an AAV-based vector carrying an multi-characteristic opsin (MCO) gene cassette, is being tested for retinitis pigmentosa.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
March 26, 2024
Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MCO-010 (sonpiretigene isteparvovec) is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy for vision restoration in advanced retinitis pigmentosa (RP).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
March 30, 2023
Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Recipient : Charles River Laboratories, Inc
Deal Size : Undisclosed
Deal Type : Partnership
Details : Through this partnership, Nanoscope will have access to established manufacturing platforms and multiple Charles River CDMO centers of excellence. The vMCO-010 is an adeno-associated virus serotype 2-based vector carried multi-characteristic opsin gene e...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
October 18, 2022
Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Recipient : Charles River Laboratories, Inc
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : This multicenter, randomized, double-masked, sham-controlled, dose-ranging study will evaluate 2 dose levels of vMCO-010 in up to 18 subjects with retinitis pigmentosa (9 per dose).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
September 13, 2022
Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MCO-020
Therapeutic Area : Ophthalmology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Nanoscope Therapeutics to Present at the 3rd Annual Gene Therapy for Ophthalmic Disorders Meeting
Details : Nanoscope’s MCO-020 gene therapy program is based on targeted laser-delivery of optogenes to areas of geographic atrophy in advanced AMD patients, and currently undergoing IND-enabling studies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
September 08, 2022
Lead Product(s) : MCO-020
Therapeutic Area : Ophthalmology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Nanoscope Announces Presentations at the 22nd Euretina Congress
Details : The purpose of the study is to evaluate the safety and efficacy of a single intravitreal injection of virally-carried Multi-Characteristic Opsin (vMCO-010).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
August 29, 2022
Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Nanoscope Therapeutics to Present at the Retina Forum 2022
Details : This multicenter, randomized, double-masked, sham-controlled, dose-ranging study will evaluate 2 dose levels of vMCO-010 in up to 18 subjects with retinitis pigmentosa (9 per dose). Nine subjects will receive sham injection.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
August 26, 2022
Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VMCO-010 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Stargardt Disease.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
June 14, 2022
Lead Product(s) : vMCO-010
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : vMCO-010, an investigational AAV gene therapy designed to restore functional vision to patients with severe vision loss due to retinal degeneration, demonstrated a favorable safety profile and several patients experienced restoration of vision in Phase 1...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
April 26, 2022
Lead Product(s) : Sonpiretigene Isteparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
