
 
													 
									 
															 
															Year
 
															DEALS // DEV.
 
															Country
 
															 
															Therapeutic Area
 
															Study Phase
 
															Deal Type
 
															Product Type
 
															Dosage Form
 
															Lead Product
 
															Target

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The new patent covers a method of treating cancer by intratumoral administration of large surface area microparticle (LSAM) taxanes in combination with systemic administration of immune checkpoint inhibitors (ICIs).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
March 07, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : No dose limiting toxicities, treatment-related serious adverse events, or clinically significant laboratory changes were reported. Systemic paclitaxel concentration did not exceed 3.5 ng/mL at any timepoint measured supporting the lack of systemic toxici...
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
December 20, 2022
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NanoPac (LSAM paclitaxel) is very small particles of the chemotherapy drug, paclitaxel, which is administered intravenously in a number of types of cancer.
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
November 11, 2022
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Docetaxel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
NanOlogy Publishes Review Article of Preclinical and Clinical Research Supporting LSAM-DTX
Details : LSAM-DTX (docetaxel) is retained in the tumor for continuous drug release after intratumoral injection in a range of solid tumor preclinical models and in combination with an immune checkpoint inhibitor demonstrated synergy in a preclinical metastatic br...
Product Name : LSAM-DTX
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
September 20, 2022
Lead Product(s) : Docetaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Docetaxel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In this Phase 1/2 clinical trial, NanoDoce (Docetaxel/LSAM-DTX) showed promising signs of preventing disease progression and interesting immunogenic effects with minimal adverse events.
Product Name : LSAM-DTX
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
August 01, 2022
Lead Product(s) : Docetaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SOR007 (paclitaxel) was well tolerated at all concentrations allowing 2.0% concentration to continue to dose expansion phase of trial. No confirmed adverse events were recorded, local skin reactions were minor, and systemic absorption of paclitaxel was n...
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
May 03, 2022
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : US Biotest
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NanoPac has been well tolerated in this trial to date with no confirmed drug-related systemic adverse events and transient mild/moderate abdominal pain as the primary local adverse event. No pancreatitis has been reported.
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
November 09, 2021
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : US Biotest
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NanoPac is composed of large surface area microparticles of pure paclitaxel designed as a drug depot for local administration and sustained drug release over several weeks.
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
June 09, 2021
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : 0.15%, 1.0% and 2.0% concentrations of SOR007 were evaluated applied twice daily to one or more 50 cm2 treatment areas per subject for 28 or 56 days. SOR007 was well tolerated at all concentrations allowing the 2.0% to continue to the dose expansion pha...
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
December 29, 2020
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NanOlogy has enrolled the first patient in a Phase 2 clinical trial of NanoPac® (sterile nanoparticulate paclitaxel) for suspension via intratumoral injection for local prostate cancer.
Product Name : NanoPac
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
November 04, 2020
Lead Product(s) : Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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