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    [{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"LBL-024","moa":"4-1BB\/PDL1","graph1":"Oncology","graph2":"Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Leads Biolabs \/ Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital","highestDevelopmentStatusID":"8","companyTruncated":"Leads Biolabs \/ Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital"},{"orgOrder":0,"company":"Leads 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First Affiliated Hospital of Nanchang University | The First Affiliated Hospital of Bengbu Medical University","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"LBL-015","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Leads Biolabs \/ Shanghai East Hospital | Shandong Cancer Hospital and Institute | Henan Cancer Hospital | Hunan Cancer Hospital | The First Affiliated Hospital of Nanchang University | The First Affiliated Hospital of Bengbu Medical University","highestDevelopmentStatusID":"7","companyTruncated":"Leads Biolabs \/ Shanghai East Hospital | Shandong Cancer Hospital and Institute | Henan Cancer Hospital | Hunan Cancer Hospital | The First Affiliated Hospital of Nanchang 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Institute","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"LBL-003","moa":"CD33","graph1":"Oncology","graph2":"Phase I","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Leads Biolabs \/ Henan Cancer Hospital | Hunan Cancer Hospital | Shandong Cancer Hospital and Institute","highestDevelopmentStatusID":"6","companyTruncated":"Leads Biolabs \/ Henan Cancer Hospital | Hunan Cancer Hospital | Shandong Cancer Hospital and Institute"}]

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                            01

                            Leads Biolabs

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                            Lead Product(s) : LBL-024

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 20, 2025

                            Lead Product(s) : LBL-024

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Leads Biolabs

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                            Lead Product(s) : LBL-024,Etoposide

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Leads Biolabs Earns FDA Orphan Status for LBL-024 in Neuroendocrine Cancer

                            Details : LBL-024 is a tetravalent bispecific antibody that simultaneously targets PD-L1 and 4-1BB, serving dual functions. It is being evaluated for the treatment of neuroendocrine cancer.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            November 22, 2024

                            Lead Product(s) : LBL-024,Etoposide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : LBL-024,Cisplatin,Etoposide

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Leads Biolabs' LBL-024 Receives Breakthrough Designation in China

                            Details : LBL-024 is a bispecific antibody, binds to PD-L1 with high affinity, blocking the PD-L1/PD-1 pathway while activating the 4-1BB pathway in the tumor microenvironment.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 10, 2024

                            Lead Product(s) : LBL-024,Cisplatin,Etoposide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

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                            Lead Product(s) : LBL-034

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Leads Biolabs Receives Orphan Drug Designation for LBL-034 in Multiple Myeloma

                            Details : LBL-034, a humanized bispecific T-cell engaging antibody targeting both GPRC5D and CD3 which is being developed by Leads Biolabs for treatment of multiple myeloma (MM).

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 11, 2024

                            Lead Product(s) : LBL-034

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

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                            Lead Product(s) : LBL-024

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CDE Approves Pivotal Study of LBL-024, an Anti-PD-L1/4-1BB Bispecific Antibody

                            Details : LBL-024 is a bispecific antibody targeting PD-L1 and 4-1BB, blocking immunosuppression while activating the costimulatory pathway in tumors.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 30, 2024

                            Lead Product(s) : LBL-024

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

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                            Lead Product(s) : LBL-024

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Clinical Trial of LBL-024 Combined With Etoposide and Platinum in Patients With Advanced Neuroendocrine Carc...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 06, 2023

                            Lead Product(s) : LBL-024

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

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                            Lead Product(s) : LBL-034

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase I/II Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 22, 2023

                            Lead Product(s) : LBL-034

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

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                            Lead Product(s) : LBL-007,Toripalimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Chime Biologics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Chime Biologics Announces Strategic Cooperation with Leads Biolabs and BeiGene to Advance LBL-007 mAb Developm...

                            Details : The agreement aims to accelerate LBL-007, a novel antibody targeting the LAG-3 pathway, development and manufacturing for speedy clinical advancement for solid tumors.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            June 30, 2023

                            Lead Product(s) : LBL-007,Toripalimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Chime Biologics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

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                            Lead Product(s) : LBL-033

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The U.S. FDA Approved the Phase I/II Clinical Trial Application to Evaluate LBL-033, An Anti-MUC16/CD3 Bispeci...

                            Details : LBL-033 is a T-cell engager, bispecific antibody, targeting MUC16-expressing tumor cells and CD3-expressing T cells, which is investigated for treatment for advanced solid tumors including ovarian cancer.

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            June 16, 2023

                            Lead Product(s) : LBL-033

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

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                            Lead Product(s) : LBL-033

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            March 22, 2023

                            Lead Product(s) : LBL-033

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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