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Biolabs","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Leads Biolabs \/ Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital","highestDevelopmentStatusID":"8","companyTruncated":"Leads Biolabs \/ Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"LBL-024","moa":"4-1BB\/PDL1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Leads Biolabs \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Leads Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"LBL-024","moa":"4-1BB\/PDL1","graph1":"Oncology","graph2":"Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Leads Biolabs \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Leads Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody, Unconjugated","year":"2024","type":"Inapplicable","leadProduct":"Etoposide","moa":"||4-1BB\/PDL1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Leads Biolabs \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Leads Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody, Unconjugated","year":"2024","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||4-1BB\/PDL1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Leads Biolabs \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Leads Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody, 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\/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"LBL-047","moa":"BDCA2\/TACI","graph1":"Immunology","graph2":"Phase I","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Leads Biolabs \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Leads Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Dianthus Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"CHINA","productType":"Protein","year":"2025","type":"Licensing Agreement","leadProduct":"DNTH212","moa":"APRIL\/BAFF\/BDCA2","graph1":"Immunology","graph2":"IND Enabling","graph3":"Leads 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                          01

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-024 (Opamtistomig) is a Antibody drug, which is currently being evaluated in Phase II clinical studies for the treatment of Neoplasms.

                          Product Name : LBL-024

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          January 09, 2026

                          Lead Product(s) : Opamtistomig,Cisplatin,Paclitaxel,Fluorouracil,Capecitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Peking University Cancer Hospital & Institute

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-047 is a Protein drug, which is currently being evaluated in Phase I clinical studies for the treatment of Lupus Erythematosus, Systemic.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 07, 2026

                          Lead Product(s) : LBL-047

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Shanghai Public Health Clinical Center

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Lead Product(s) : Opamtistomig,Paclitaxel

                          Therapeutic Area : Oncology

                          Study Phase : Phase I/ Phase II

                          Sponsor : The First Affiliated Hospital with Nanjing Medical University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : LBL-024 (Opamtistomig) is a antibody candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Triple Negative Breast Neoplasms.

                          Product Name : LBL-024

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          December 15, 2025

                          Lead Product(s) : Opamtistomig,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : The First Affiliated Hospital with Nanjing Medical University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : Through the licensing deal for DNTH212, undisclosed company aims to target APRIL/BAFF/BDCA2 in severe autoimmune diseases.

                          Product Name : DNTH212

                          Product Type : Protein

                          Upfront Cash : $30.0 million

                          October 16, 2025

                          Lead Product(s) : DNTH212

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Dianthus Therapeutics

                          Deal Size : $1,000.0 million

                          Deal Type : Licensing Agreement

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                          05

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-047 is a bispecific fusion protein composed of a humanized anti-blood dendritic cell antigen 2 (BDCA2) antibody and an engineered transmembrane activator and CAML interactor.

                          Product Name : LBL-047

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 22, 2025

                          Lead Product(s) : LBL-047

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          August 08, 2025

                          Lead Product(s) : LBL-024,Durvalumab,Cisplatin,Gemcitabine,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Shanghai Zhongshan Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Melanoma.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          August 01, 2025

                          Lead Product(s) : LBL-024,LBL-007,Toripalimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Ovarian Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          June 29, 2025

                          Lead Product(s) : LBL-024,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Lead Product(s) : LBL-024,Docetaxel,Bevacizumab

                          Therapeutic Area : Oncology

                          Study Phase : Phase II

                          Sponsor : Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          January 20, 2025

                          Lead Product(s) : LBL-024,Docetaxel,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Sun Yat-sen University | Mianyang Central Hospital | Xiangyang Central Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          IPPE
                          Not Confirmed
                          IPPE
                          Not Confirmed

                          Details : LBL-024 is a tetravalent bispecific antibody that simultaneously targets PD-L1 and 4-1BB, serving dual functions. It is being evaluated for the treatment of neuroendocrine cancer.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          November 22, 2024

                          Lead Product(s) : LBL-024,Etoposide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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