
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : DNTH212
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Dianthus Therapeutics
Deal Size : $1,000.0 million
Deal Type : Licensing Agreement
Dianthus Therapeutics Licenses DNTH212 for Severe Autoimmune Diseases from Leads Biolabs
Details : Through the licensing deal for DNTH212, undisclosed company aims to target APRIL/BAFF/BDCA2 in severe autoimmune diseases.
Product Name : DNTH212
Product Type : Protein
Upfront Cash : $30.0 million
October 16, 2025
Lead Product(s) : DNTH212
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Dianthus Therapeutics
Deal Size : $1,000.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : LBL-047
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Clears IND for LBL-047, an Anti-BDCA2/TACI Bispecific Fusion Protein by Leads Biolabs
Details : LBL-047 is a bispecific fusion protein composed of a humanized anti-blood dendritic cell antigen 2 (BDCA2) antibody and an engineered transmembrane activator and CAML interactor.
Product Name : LBL-047
Product Type : Protein
Upfront Cash : Inapplicable
September 22, 2025
Lead Product(s) : LBL-047
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

LBL-024 Combination Drug in Advanced Solid Tumors Substudy 02 (BTC & HCC)
Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 08, 2025

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Lead Product(s) : LBL-024
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Trial of LBL-024 Alone or with LBL-007/Toripalimab in Advanced Melanoma Patients
Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Melanoma.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 01, 2025
Lead Product(s) : LBL-024
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : LBL-024
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase Ib/II Trial of LBL-024 with Paclitaxel in Platinum-Resistant Ovarian Cancer Patients
Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Ovarian Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 29, 2025
Lead Product(s) : LBL-024
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : LBL-024 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
January 20, 2025

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Lead Product(s) : LBL-024,Etoposide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Leads Biolabs Earns FDA Orphan Status for LBL-024 in Neuroendocrine Cancer
Details : LBL-024 is a tetravalent bispecific antibody that simultaneously targets PD-L1 and 4-1BB, serving dual functions. It is being evaluated for the treatment of neuroendocrine cancer.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 22, 2024
Lead Product(s) : LBL-024,Etoposide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : LBL-034
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Leads Biolabs Receives Orphan Drug Designation for LBL-034 in Multiple Myeloma
Details : LBL-034, a humanized bispecific T-cell engaging antibody targeting both GPRC5D and CD3 which is being developed by Leads Biolabs for treatment of multiple myeloma (MM).
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 06, 2024
Lead Product(s) : LBL-034
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : LBL-024,Cisplatin,Etoposide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Leads Biolabs' LBL-024 Receives Breakthrough Designation in China
Details : LBL-024 is a bispecific antibody, binds to PD-L1 with high affinity, blocking the PD-L1/PD-1 pathway while activating the 4-1BB pathway in the tumor microenvironment.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 10, 2024
Lead Product(s) : LBL-024,Cisplatin,Etoposide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : LBL-024
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
CDE Approves Pivotal Study of LBL-024, an Anti-PD-L1/4-1BB Bispecific Antibody
Details : LBL-024 is a bispecific antibody targeting PD-L1 and 4-1BB, blocking immunosuppression while activating the costimulatory pathway in tumors.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 30, 2024
Lead Product(s) : LBL-024
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
