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[{"orgOrder":0,"company":"Nanite","sponsor":"CMT Research Foundation","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"CMT Research Foundation and Nanite Inc. Announce Partnership to Enhance Therapeutic Efficacy of Antisense Oligonucleotides in CMT1A","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Discovery","country":"U.S.A","productType":"Large molecule","productStatus":"Undisclosed","date":"February 2023","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Discovery"},{"orgOrder":0,"company":"Nanite","sponsor":"CF Foundation","pharmaFlowCategory":"D","amount":"$2.0 million","upfrontCash":"Undisclosed","newsHeadline":"Nanite Inc. Receives Up to $2M Investment from CF Foundation to Explore a Novel Method to Deliver Genetic Therapies to the Lung","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Preclinical","country":"U.S.A","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"March 2023","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Preclinical"}]

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            Details:

            With the new funding from the Foundation, Nanite will work on initially developing polymer nanoparticles that can accurately deliver mRNA therapies to the lung while potentially better resisting the thick, sticky mucus that clogs the lungs of patients with CF.

            Lead Product(s): m-RNA Therapy

            Therapeutic Area: Genetic Disease Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: CF Foundation

            Deal Size: $2.0 million Upfront Cash: Undisclosed

            Deal Type: Funding March 15, 2023

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            Under the terms of the partnership, Nanite will design delivery vehicles for genetic medicines to Schwann cells via PNPs, an emerging technology for drug delivery to hard-to-hit targets and to enhance therapeutic efficacy of antisense oligonucleotides in CMT1A.

            Lead Product(s): Antisense Oligonucleotide

            Therapeutic Area: Genetic Disease Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Large molecule

            Partner/Sponsor/Collaborator: CMT Research Foundation

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership February 22, 2023

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